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DIDREX (benzphetamine) Tablets are indicated in the management of exogenous obesity as a short term (a few weeks) adjunct in a regimen of weight reduction based on caloric restriction in patients with an initial body mass index (BMI) of 30 kg/m² or higher who have not responded to appropriate weight reducing regimen (diet and/or exercise) alone. Below is a chart of Body Mass Index (BMI) based on various heights and weights. BMI is calculated by taking the patient's weight, in kilograms (kg), divided by the patient's height, in meters (m), squared. Metric conversions are as follows: pounds ÷ 2.2 = kg; inches × 0.0254 = meters. The limited usefulness of agents of this class (See CLINICAL PHARMACOLOGY) should be weighed against possible risks inherent in their use such as those described below.
BODY MASS INDEX (BMI), kg/m²
|Weight (pounds)||Height (feet, inches)|
DIDREX (benzphetamine) Tablets are indicated for use as monotherapy only.
DOSAGE AND ADMINISTRATION
Dosage should be individualized according to the response of the patient. The suggested dosage ranges from 25 to 50 mg one to three times daily. Treatment should begin with 25 to 50 mg once daily with subsequent increase in individual dose or frequency according to response. A single daily dose is preferably given in mid-morning or mid-afternoon, according to the patient's eating habits. In an occasional patient it may be desirable to avoid late afternoon administration. Use of benzphetamine hydrochloride is not recommended in individuals under 12 years of age.
DIDREX (benzphetamine) Tablets are supplied as follows:
50 mg (peach, round, imprinted with DIDREX (benzphetamine) 50, scored)
Bottles of 100 NDC 0009-0024-01
Bottles of 500 NDC 0009-0024-02
Store at controlled room temperature 20° to 25° C (68° to 77° F). [see USP]
Distributed by: Pharmacia & Upjohn Company. Division of Pfizer Inc, NY, NY 10017. Manufactured by: MOVA Pharmaceuticals Manati, PR 00674. August 2009This monograph has been modified to include the generic and brand name in many instances.
Last reviewed on RxList: 2/26/2010
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