"By Peter Russell
WebMD Health News
Brunilda Nazario, MD
April 20, 2015 -- A one-size-fits-all approach to treating obesity doesn't work because obese people fall into one of six groups, a study says."...
The following have been associated with the use of benzphetamine hydrochloride:
Palpitation, tachycardia, elevation of blood pressure.
Valvular heart disease associated with the use of some anorectic agents such as fenfluramine and dexfenfluramine, both independently and especially when used in combination with other anorectic drugs, have been reported. However, no cases of this valvulopathy have been reported when DIDREX Tablets have been used alone.
Overstimulation, restlessness, dizziness, insomnia, tremor, sweating, headache; rarely, psychotic episodes at recommended doses; depression following withdrawal of the drug.
Dryness of the mouth, unpleasant taste, nausea, diarrhea, other gastrointestinal disturbances.
Urticaria and other allergic reactions involving the skin.
Changes in libido.
Read the Didrex (benzphetamine) Side Effects Center for a complete guide to possible side effects
Efficacy of DIDREX Tablets in combination with other anorectic agents has not been studied and the combined use may have the potential for serious cardiac problems.
Hypertensive crises have resulted when sympathomimetic amines have been used concomitantly or within 14 days following use of monoamine oxidase inhibitors. DIDREX should not be used concomitantly with other CNS stimulants.
Urinary alkalinizing agents increase blood levels and decrease excretion of amphetamines. Urinary acidifying agents decrease blood levels and increase excretion of amphetamines.
Drug Abuse And Dependence
Benzphetamine is a controlled substance under the Controlled Substance Act by the Drug Enforcement Administration and has been assigned to Schedule III.
Benzphetamine hydrochloride is related chemically and pharmacologically to the amphetamines. Amphetamines and related stimulant drugs have been extensively abused, and the possibility of abuse of DIDREX Tablets should be kept in mind when evaluating the desirability of including a drug as part of a weight reduction program. Abuse of amphetamines and related drugs may be associated with intense psychological dependence and severe social dysfunction. There are reports of patients who have increased the dosage to many times that recommended. Abrupt cessation following prolonged high dosage administration results in extreme fatigue and mental depression; changes are also noted on the sleep EEG. Manifestations of chronic intoxication with anorectic drugs include severe dermatoses, marked insomnia, irritability, hyperactivity, and personality changes. The most severe manifestation of chronic intoxication is psychosis, often clinically indistinguishable from schizophrenia.
Read the Didrex Drug Interactions Center for a complete guide to possible interactions
Last reviewed on RxList: 1/9/2017
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