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(etidronate disodium) Tablets
Didronel® tablets contain 400 mg of etidronate disodium, the disodium salt of (1hydroxyethylidene) diphosphonic acid, for oral administration. This compound, also known as EHDP, regulates bone metabolism. It is a white powder, highly soluble in water, with a molecular weight of 250 and the following structural formula:
Each tablet contains magnesium stearate, microcrystalline cellulose, and starch.
What are the possible side effects of etidronate (Didronel)?
Get emergency medical help if you have any of these signs of an allergic reaction: hives; difficulty breathing; swelling of your face, lips, tongue, or throat.
Stop using etidronate and call your doctor at once if you have any of these serious side effects:
- painful or difficult swallowing;
- severe heartburn, burning pain in your upper stomach, or coughing up blood;
- severe joint, bone, or muscle pain;
- jaw pain, numbness, or swelling;
- severe diarrhea;
- bone fracture; or
- a red, blistering, peeling skin rash.
What are the precautions when taking etidronate disodium (Didronel)?
Before taking etidronate, tell your doctor or pharmacist if you are allergic to it; or to other bisphosphonates (such as alendronate); or if you have any other allergies. This product may contain inactive ingredients, which can cause allergic reactions or other problems. Talk to your pharmacist for more details.
This medication should not be used if you have certain medical conditions. Before using this medicine, consult your doctor or pharmacist if you have: a certain bone disorder that causes soft/painful bones (osteomalacia).
Before using this medication, tell your doctor or pharmacist your medical history, especially of: kidney disease, inability to sit upright or stand for at least 30 minutes, difficult/painful swallowing, esophagus problems (such as esophageal...
Last reviewed on RxList: 4/13/2015
This monograph has been modified to include the generic and brand name in many instances.
Additional Didronel Information
Report Problems to the Food and Drug Administration
You are encouraged to report negative side effects of prescription drugs to the FDA. Visit the FDA MedWatch website or call 1-800-FDA-1088.
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