"A deeper dive into data from the Trial Evaluating Cardiovascular Outcomes With Sitagliptin (TECOS) with the type 2 diabetes drug sitagliptin (Januvia, Merck), confirming that the dipeptidyl peptidase-4 (DPP-4) is not associated with any "...
(Generic versions may still be available.)
DOSAGE AND ADMINISTRATION
Given cyclically for short term use only:
The lowest dose that will control symptoms should be chosen and medication should be discontinued as promptlyas possible.
Attempts to discontinue or taper medication should be made at 3 to 6 month intervals.
The usual dosage range is one or two applicatorsful per day for one or two weeks, then gradually reduced to one half initial dosage for a similar period. A maintenance dosage of one applicatorful, one to three times a week, may be used after restoration of the vaginal mucosa has been achieved.
Treated patients with an intact uterus should be monitored closely for signs of endometrial cancer and appropriate diagnostic measures should be taken to rule out malignancy in the event of persistent or recurring abnormal vaginal bleeding.
Available in 2.75 oz. (78g) tubes with or without ORTHO* Measured Dose Applicator, 5g.
- With applicator: NDC 0062-5450-77
- Without applicator: NDC 0062-5450-00
Store at controlled room temperature.This monograph has been modified to include the generic and brand name in many instances.
Last reviewed on RxList: 1/29/2005
Additional Dienestrol Information
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