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Dienestrol Side Effects Center
Medical Editor: John P. Cunha, DO, FACOEP
Ortho Dienestrol Cream (dienestrol) is a form of the female hormone estrogen used to treat atrophic vaginitis and kraurosis vulvae. The brand name of this medication is discontinued, but generic versions may be available. Common side effects include vaginal irritation, dizziness, lightheadedness, headache, stomach upset, bloating, nausea, weight changes, increased/decreased interest in sex, and breast tenderness.
The lowest dose of Ortho Dienestrol Cream that will control symptoms should be chosen and medication should be discontinued as promptly as possible. Ortho Dienestrol Cream may interact with other drugs. Tell your doctor all medications and supplements you use. Estrogens may cause fetal harm when administered to a pregnant woman. Ortho Dienestrol Cream is not recommended for use during pregnancy. It is unknown if this drug passes into breast milk. Consult your doctor before breastfeeding.
Our Ortho Dienestrol Cream (dienestrol) Side Effects Drug Center provides a comprehensive view of available drug information on the potential side effects when taking this medication.
This is not a complete list of side effects and others may occur. Call your doctor for medical advice about side effects. You may report side effects to FDA at 1-800-FDA-1088.
What is Patient Information Overview?
A concise overview of the drug for the patient or caregiver from First DataBank.
Dienestrol Overview - Patient Information: Side Effects
In the US -
Call your doctor for medical advice about side effects. You may report side effects to FDA at 1-800-FDA-1088.
In Canada - Call your doctor for medical advice about side effects. You may report side effects to Health Canada at 1-866-234-2345.
Read the entire patient information overview for Dienestrol (Dienestrol)
What is Prescribing information?
The FDA package insert formatted in easy-to-find categories for health professionals and clinicians.
Dienestrol FDA Prescribing Information: Side Effects
(See WARNINGS regarding induction of neoplasia, adverse effects on the fetus, increased incidence of gall bladder disease, and adverse effects similar to those of oral contraceptives, including thromboembolism.) The following additional adverse reactions have been reported with estrogenic therapy, including oral contraceptives:
1. Genitourinary system.
- Increase in size of uterine fibromyomata.
- Vaginal candidiasis.
- Breakthrough bleeding, spotting, change in menstrual flow.
- Dysmenorrhea. Premenstrual-like syndrome.
- Amenorrhea during and after treatment.
- Change in cervical eversion and in degree of cervical secretion.
- Cystitis-like syndrome.
Tenderness, enlargement, secretion.
- Cholestatic jaundice.
- Nausea, vomiting.
- Abdominal cramps, bloating.
- Erythema multiforme.
- Erythema nodosum.
- Hemorrhagic eruption.
- Loss of scalp hair.
- Chloasma or melasma which may persist when drug is discontinued.
- Steepening of corneal curvature.
- Intolerance to contact lenses.
- Reduced carbohydrate tolerance.
- Aggravation of porphyria.
- Changes in libido.
- Increase or decrease in weight.
Read the entire FDA prescribing information for Dienestrol (Dienestrol)
Additional Dienestrol Information
Report Problems to the Food and Drug Administration
You are encouraged to report negative side effects of prescription drugs to the FDA. Visit the FDA MedWatch website or call 1-800-FDA-1088.
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