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Differin Lotion .1

What is acne?

Acne (acne vulgaris, common acne) is a disease of the hair follicles of the face, chest, and back that affects almost all males and females during puberty; the only exception being teenage members of a few primitive isolated tribes living in Neolithic societies. It is not caused by bacteria, although bacteria play a role in its development. It is not unusual for some women to develop acne in their mid- to late-20s.

Acne appears on the skin as...

  • congested pores ("comedones"), also known as blackheads or whiteheads,
  • tender red bumps also known as pimples or zits,
  • pustules, and occasionally as
  • cysts (deep pimples, boils).

You can do a lot to treat your acne using products available at a drugstore or cosmetic counter that do not require a prescription. However, for tougher cases of acne, you should consult a physician for treatment options.

What...

Differin Lotion .1

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DIFFERIN®
(adapalene) Lotion 0.1%

For topical use only

DRUG DESCRIPTION

DIFFERIN (adapalene) Lotion, 0.1% for topical use, is an adapalene-based product.

Adapalene is a naphthoic acid derivative with retinoid-like properties. The chemical name for adapalene is (6-[3-(1-adamantyl)-4-methoxyphenyl]-2-naphthoic acid). Adapalene has the following structural formula:

Adapalene:

DIFFERIN® (adapalene) Structural Formula Illustration

Molecular formula: C28H28O3 Molecular weight: 412.5

DIFFERIN (adapalene lotion .1%) Lotion contains the following inactive ingredients: carbomer 941, disodium edetate, medium chain triglycerides, methylparaben, phenoxyethanol, poloxamer 124, polyoxyl-6polyoxyl-32 palmitostearate, PPG-12 / SMDI copolymer, propylene glycol, propylparaben, sodium hydroxide, stearyl alcohol, and purified water.

Last reviewed on RxList: 4/1/2010
This monograph has been modified to include the generic and brand name in many instances.

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