"On April 1, 2013, the World Health Organization (WHO) first reported 3 human infections with a new influenza A (H7N9) virus in China. Since then, additional cases have been reported. Most reported cases have severe respiratory illness and, in som"...
Fluconazole, USP, the first of a new subclass of synthetic triazole antifungal agents, is available as tablets for oral administration.
Fluconazole, USP is designated chemically as 2,4-Difluoro-1',1'-bis(1H-1,2,4-triazol-1-ylmethyl) benzyl alcohol and has the following structural formula:
C13H12F2N6O M.W. 306.27
Fluconazole, USP is a white crystalline solid which is slightly soluble in water and saline.
Fluconazole Tablets USP, for oral administration, contain 50, 100, 150, or 200 mg of fluconazole, USP and have the following inactive ingredients: colloidal silicon dioxide, corn starch, croscarmellose sodium, FD&C red #40 aluminum lake, lactose monohydrate, magnesium stearate, microcrystalline cellulose, and talc.
What are the possible side effects of fluconazole (Diflucan)?
Get emergency medical help if you have any of these signs of an allergic reaction: hives; difficult breathing; swelling of your face, lips, tongue, or throat.
Call your doctor at once if you have any of these serious side effects:
- nausea, upper stomach pain, itching, loss of appetite, dark urine, clay-colored stools, jaundice (yellowing of the skin or eyes);
- fever, chills, body aches, flu symptoms;
- severe blistering, peeling, and red skin rash;
- easy bruising or bleeding, unusual weakness; or
- seizure (convulsions).
What are the precautions when taking fluconazole (Diflucan)?
Before taking fluconazole, tell your doctor or pharmacist if you are allergic to it; or to other azole antifungal drugs (such as ketoconazole, itraconazole); or if you have any other allergies. This product may contain inactive ingredients, which can cause allergic reactions or other problems. Talk to your pharmacist for more details.
Before using this medication, tell your doctor or pharmacist your medical history, especially of: liver disease, kidney disease.
Fluconazole may cause a condition that affects the heart rhythm (QT prolongation). QT prolongation can infrequently result in serious (rarely fatal) fast/irregular heartbeat and other symptoms (such as severe dizziness, fainting) that need medical attention right away.
The risk of QT prolongation may be...
Last reviewed on RxList: 1/7/2016
This monograph has been modified to include the generic and brand name in many instances.
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