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Digibind Side Effects Center
Medical Editor: John P. Cunha, DO, FACOEP
Digibind (digoxin immune fab) is used as an antidote to treat a life-threatening overdose of digoxin or digitoxin. It is not for treating a mild digitalis overdose. This medication may be available in generic form. Side effects are uncommon. Serious side effects include fever, high potassium (slow heart rate, weak pulse, muscle weakness, tingly feeling), low potassium (confusion, uneven heart rate, extreme thirst, increased urination, leg discomfort, muscle weakness or limp feeling), feeling short of breath even with mild exertion, or swelling, rapid weight gain.
The dosage of Digibind varies according to the amount of digoxin (or digitoxin) to be neutralized. The average dose used during clinical testing was 10 vials. It is only administered under a physician's supervision in emergency situations. Other drugs may interact with Digibind. Tell your doctor all prescription and over-the-counter medications and supplements you use. During pregnancy, Digibind should be taken only if prescribed. It may be harmful to a fetus. It is unknown if this drug passes into breast milk or if it could harm a nursing baby. Consult your doctor before breast-feeding.
Our Digibind (digoxin immune fab) Side Effects Drug Center provides a comprehensive view of available drug information on the potential side effects when taking this medication.
This is not a complete list of side effects and others may occur. Call your doctor for medical advice about side effects. You may report side effects to FDA at 1-800-FDA-1088.
What is Patient Information in Detail?
Easy-to-read and understand detailed drug information and pill images for the patient or caregiver from Cerner Multum.
Digibind in Detail - Patient Information: Side Effects
Get emergency medical help if you have any of these signs of an allergic reaction: hives; difficulty breathing; swelling of your face, lips, tongue, or throat.
Tell your caregivers at once if you have any of these serious side effects:
- high potassium (slow heart rate, weak pulse, muscle weakness, tingly feeling);
- low potassium (confusion, uneven heart rate, extreme thirst, increased urination, leg discomfort, muscle weakness or limp feeling);
- feeling short of breath, even with mild exertion; or
- swelling, rapid weight gain.
This is not a complete list of side effects and others may occur. Tell your doctor about any unusual or bothersome side effect. You may report side effects to FDA at 1-800-FDA-1088.
Read the entire detailed patient monograph for Digibind (Digoxin Immune Fab)
What is Prescribing information?
The FDA package insert formatted in easy-to-find categories for health professionals and clinicians.
Digibind FDA Prescribing Information: Side Effects
Allergic reactions to DIGIBIND (digoxin immune fab) have been reported rarely. Patients with a history of allergy, especially to antibiotics, appear to be at particular risk (see WARNINGS). In a few instances, low cardiac output states and congestive heart failure could have been exacerbated by withdrawal of the inotropic effects of digitalis. Hypokalemia may occur from re-activation of (sodium, potassium) ATPase (see Laboratory Tests). Patients with atrial fibrillation may develop a rapid ventricular response from withdrawal of the effects of digitalis on the atrioventricular node.4
Read the entire FDA prescribing information for Digibind (Digoxin Immune Fab)
Additional Digibind Information
Report Problems to the Food and Drug Administration
You are encouraged to report negative side effects of prescription drugs to the FDA. Visit the FDA MedWatch website or call 1-800-FDA-1088.
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