May 29, 2016

Diindolylmethane

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How does Diindolylmethane work?

Diindolylmethane might act like estrogen in the body, but there is evidence that under certain circumstances it might also block estrogen effects.

Are there safety concerns?

Diindolylmethane is LIKELY SAFE when consumed in the small amounts found in foods. A typical diet supplies 2-24 mg of diindolylmethane. It is POSSIBLY SAFE for most people when taken by mouth short-term for medicinal purposes. Taking larger doses of diindolylmethane is POSSIBLY UNSAFE. Taking 600 mg of diindolylmethane daily has been reported to lower sodium levels in some people.

Special Precautions & Warnings:

Pregnancy and breast-feeding: Diindolylmethane is LIKELY SAFE when consumed in the small amounts found in foods. But don't take larger amounts. Not enough is known about the safety of larger amounts during pregnancy and breast-feeding.

Children: Diindolylmethane is LIKELY SAFE when consumed in the small amounts found in foods. But don't give children larger amounts. Not enough is known about the safety of larger amounts of diindolylmethane when given to children.

Hormone-sensitive conditions such as breast cancer, uterine cancer, ovarian cancer, endometriosis, or uterine fibroids: Diindolylmethane might act like estrogen, so there is some concern that it might make hormone-sensitive conditions worse. These conditions include breast, uterine, and ovarian cancer; endometriosis; and uterine fibroids. However, developing research also suggests that diindolylmethane might work against estrogen and could possibly be protective against hormone-dependent cancers. But stay on the safe side. Until more is known, don't use diindolylmethane if you have a hormone-sensitive condition.


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