In this Article
- What other names is Diindolylmethane known by?
- What is Diindolylmethane?
- How does Diindolylmethane work?
- Are there safety concerns?
- Are there any interactions with medications?
- Dosing considerations for Diindolylmethane.
Medications changed by the liver (Cytochrome P450 1A2 (CYP1A2) substrates)
Interaction Rating: Minor Be cautious with this combination.
Talk with your health provider.
Some medications are changed and broken down by the liver. Diindolylmethane might increase how quickly the liver breaks down some medications. Taking diindolylmethane along with some medications that are changed by the liver can decrease the effectiveness of some medications. Before taking diindolylmethane, talk to your healthcare provider if you take any medications that are changed by the liver.
Some of these medications that are changed by the liver include clozapine (Clozaril), cyclobenzaprine (Flexeril), fluvoxamine (Luvox), haloperidol (Haldol), imipramine (Tofranil), mexiletine (Mexitil), olanzapine (Zyprexa), pentazocine (Talwin), propranolol (Inderal), tacrine (Cognex), theophylline, zileuton (Zyflo), zolmitriptan (Zomig), and others.
Report Problems to the Food and Drug Administration
You are encouraged to report negative side effects of prescription drugs to the FDA. Visit the FDA MedWatch website or call 1-800-FDA-1088.
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