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Dilantin Patient Information including If I Miss a Dose
In this Article
- What is phenytoin (Dilantin)?
- What are the possible side effects of phenytoin?
- What is the most important information I should know about phenytoin?
- What should I discuss with my healthcare provider before taking phenytoin?
- How should I take phenytoin?
- What happens if I miss a dose?
- What happens if I overdose?
- What should I avoid while taking phenytoin?
- What other drugs will affect phenytoin?
- Where can I get more information?
What happens if I miss a dose?
Take the missed dose as soon as you remember. Skip the missed dose if it is almost time for your next scheduled dose. Do not take extra medicine to make up the missed dose.
What happens if I overdose?
Seek emergency medical attention or call the Poison Help line at 1-800-222-1222. An overdose of phenytoin can be fatal.
Overdose symptoms may include twitching eye movements, slurred speech, loss of balance, tremor, muscle stiffness or weakness, nausea, vomiting, feeling light-headed, fainting, and slow or shallow breathing.
What should I avoid while taking phenytoin?
Drinking alcohol can increase some of the side effects of phenytoin, and can also increase your risk of seizure.
Avoid taking antacids at the same time you take phenytoin. Antacids can make it harder for your body to absorb the medication.
Phenytoin may impair your thinking or reactions. Be careful if you drive or do anything that requires you to be alert.
What other drugs will affect phenytoin?
Drugs that can increase phenytoin levels in your blood include:
- stomach acid reducers such as cimetidine (Tagamet), ranitidine (Zantac), famotidine (Pepcid), or nizatidine (Axid);
- certain sedatives (such as Librium or Valium) or antidepressants (such as Prozac);
- estrogen hormone replacement;
- chlorpromazine (Thorazine), prochlorperazine (Compazine), thioridazine (Mellaril) and other phenothiazines;
- disulfiram (Antabuse);
- methylphenidate (Ritalin, Concerta, Daytrana); and
- sulfa drugs such as Septra or Bactrim.
Drugs that can make phenytoin less effective in controlling seizures include carbamazepine (Tegretol, Epitol, Carbatrol), sucralfate (Carafate), and molindone (Moban).
Other drugs that can interact with phenytoin include:
- phenobarbital (Luminal, Solfoton), valproic acid (Depakene) or divalproex sodium (Depakote);
- steroid medicines (prednisone and others);
- antidepressants such as amitriptyline (Elavil), clomipramine (Anafranil), imipramine (Janimine, Tofranil), paroxetine (Paxil), and others;
- antibiotics such as rifampin (Rimactane, Rifadin, Rifamate) or doxycycline (Doryx, Vibramycin, Adoxa, and others);
- digoxin (digitalis, Lanoxin), furosemide (Lasix); and
- theophylline (Elixophyllin, Theo-Dur, Theo-Bid, Theolair, Uniphyl).
Where can I get more information?
Your pharmacist can provide more information about phenytoin.
Remember, keep this and all other medicines out of the reach of children, never share your medicines with others, and use this medication only for the indication prescribed.
Every effort has been made to ensure that the information provided by Cerner Multum, Inc. ('Multum') is accurate, up-to-date, and complete, but no guarantee is made to that effect. Drug information contained herein may be time sensitive. Multum information has been compiled for use by healthcare practitioners and consumers in the United States and therefore Multum does not warrant that uses outside of the United States are appropriate, unless specifically indicated otherwise. Multum's drug information does not endorse drugs, diagnose patients or recommend therapy. Multum's drug information is an informational resource designed to assist licensed healthcare practitioners in caring for their patients and/or to serve consumers viewing this service as a supplement to, and not a substitute for, the expertise, skill, knowledge and judgment of healthcare practitioners. The absence of a warning for a given drug or drug combination in no way should be construed to indicate that the drug or drug combination is safe, effective or appropriate for any given patient. Multum does not assume any responsibility for any aspect of healthcare administered with the aid of information Multum provides. The information contained herein is not intended to cover all possible uses, directions, precautions, warnings, drug interactions, allergic reactions, or adverse effects. If you have questions about the drugs you are taking, check with your doctor, nurse or pharmacist.
Copyright 1996-2012 Cerner Multum, Inc. Version: 11.02. Revision date: 12/15/2010.
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