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Dilantin Infatabs

Last reviewed on RxList: 11/28/2016
Dilantin Infatabs Side Effects Center

Last reviewed on RxList 3/16/2016

Dilantin Infatabs (phenytoin) is an anti-epileptic drug (anticonvulsant) used to control seizures. Common side effects of Dilantin Infatabs include headache, nausea, vomiting, constipation, dizziness, spinning sensation, drowsiness, trouble sleeping (insomnia), nervousness, slurred speech, loss of balance or coordination, or swollen or tender gums.

The initial adult dose Dilantin Infatabs for patients who have received no previous treatment is two Infatabs three times daily. For most adults, the maintenance dosage is six to eight Infatabs daily. Pediatric dosing is determined by the child's weight. Dilantin Infatabs may interact with stomach acid reducers, sedatives, antidepressants, estrogen hormone replacement, phenothiazines, disulfiram, methylphenidate, sulfa drugs, carbamazepine, sucralfate, molindone, phenobarbital, valproic acid, divalproex sodium, steroids, antibiotics, digoxin, furosemide, or theophylline. Tell your doctor all medications and supplements you use. During pregnancy, Dilantin Infatabs should be used only when prescribed. It may harm a fetus. Since untreated seizures are a serious condition that can harm both a pregnant woman and her fetus, do not stop taking this medication unless directed by your doctor. If you are planning pregnancy, become pregnant, or think you may be pregnant, talk to your doctor about using this medication during pregnancy. Since birth control pills, patches, implants, and injections may not work if taken with this medication, discuss birth control with your doctor. This drug passes into breast milk. Consult your doctor before breastfeeding.

Our Dilantin Infatabs (phenytoin) Side Effects Drug Center provides a comprehensive view of available drug information on the potential side effects when taking this medication.

This is not a complete list of side effects and others may occur. Call your doctor for medical advice about side effects. You may report side effects to FDA at 1-800-FDA-1088.

Dilantin Infatabs Consumer Information

Get emergency medical help if you have any of these signs of an allergic reaction: hives; difficulty breathing; swelling of your face, lips, tongue, or throat. You may be more likely to have an allergic reaction if you are African-American.

Report any new or worsening symptoms to your doctor, such as: mood or behavior changes, depression, anxiety, or if you feel agitated, hostile, restless, hyperactive (mentally or physically), or have thoughts about suicide or hurting yourself.

Call your doctor at once if you have a serious side effect such as:

  • fever, swollen glands, body aches, flu symptoms;
  • skin rash, easy bruising or bleeding, severe tingling, numbness, pain, muscle weakness;
  • upper stomach pain, loss of appetite, dark urine, jaundice (yellowing of the skin or eyes);
  • chest pain, irregular heart rhythm, feeling short of breath;
  • confusion, nausea and vomiting, swelling, rapid weight gain, urinating less than usual or not at all;
  • new or worsening cough with fever, trouble breathing;
  • tremor (uncontrolled shaking), restless muscle movements in your eyes, tongue, jaw, or neck;
  • patchy skin color, red spots, or a butterfly shaped skin rash over your cheeks and nose (worsens in sunlight); or
  • severe skin reaction -- fever, sore throat, swelling in your face or tongue, burning in your eyes, skin pain, followed by a red or purple skin rash that spreads (especially in the face or upper body) and causes blistering and peeling.

Less serious side effects may include:

  • slurred speech, loss of balance or coordination;
  • swollen or tender gums; or
  • headache, dizziness, nervousness, or sleep problems (insomnia).

This is not a complete list of side effects and others may occur. Call your doctor for medical advice about side effects. You may report side effects to FDA at 1-800-FDA-1088.

Read the entire detailed patient monograph for Dilantin Infatabs (Phenytoin Tablets)

Dilantin Infatabs Professional Information

SIDE EFFECTS

Central Nervous System: The most common manifestations encountered with phenytoin therapy are referable to this system and are usually dose-related. These include nystagmus, ataxia, slurred speech, decreased coordination, and mental confusion. Dizziness, insomnia, transient nervousness, motor twitchings, and headache have also been observed.

There have also been rare reports of phenytoin-induced dyskinesias, including chorea, dystonia, tremor and asterixis, similar to those induced by phenothiazine and other neuroleptic drugs.

A predominantly sensory peripheral polyneuropathy has been observed in patients receiving long-term phenytoin therapy.

Gastrointestinal System: Nausea, vomiting, constipation, toxic hepatitis and liver damage.

Integumentary System: Dermatological manifestations sometimes accompanied by fever have included scarlatiniform or morbilliform rashes. A morbilliform rash (measles-like) is the most common; other types of dermatitis are seen more rarely. Other more serious forms which may be fatal have included bullous, exfoliative or purpuric dermatitis, lupus erythematosus, Stevens-Johnson syndrome, and toxic epidermal necrolysis (see PRECAUTIONS section).

Hemopoietic System: Hemopoietic complications, some fatal, have occasionally been reported in association with administration of phenytoin. These have included thrombocytopenia, leukopenia, granulocytopenia, agranulocytosis, and pancytopenia with or without bone marrow suppression. While macrocytosis and megaloblastic anemia have occurred, these conditions usually respond to folic acid therapy. Lymphadenopathy including benign lymph node hyperplasia, pseudolymphoma, lymphoma, and Hodgkin's disease have been reported (see WARNINGS section).

Connective Tissue System: Coarsening of the facial features, enlargement of the lips, gingival hyperplasia, hypertrichosis, and Peyronie's disease.

Immunologic: Hypersensitivity syndrome (which may include, but is not limited to, symptoms such as arthralgias, eosinophilia, fever, liver dysfunction, lymphadenopathy, or rash), systemic lupus erythematosus, periarteritis nodosa and immunoglobulin abnormalities.

Read the entire FDA prescribing information for Dilantin Infatabs (Phenytoin Tablets)

Related Resources for Dilantin Infatabs

Read the Dilantin Infatabs User Reviews »

© Dilantin Infatabs Patient Information is supplied by Cerner Multum, Inc. and Dilantin Infatabs Consumer information is supplied by First Databank, Inc., used under license and subject to their respective copyrights.

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