"According to new research on epilepsy, zebrafish have certainly earned their stripes. Results of a study in Nature Communications suggest that zebrafish carrying a specific mutation may help researchers discover treatments for Dravet syndrome "...
(extended phenytoin sodium) Capsules, USP
Phenytoin sodium is an antiepileptic drug. Phenytoin sodium is related to the barbiturates in chemical structure, but has a five-membered ring. The chemical name is sodium 5,5-diphenyl-2, 4-imidazolidinedione, having the following structural formula:
Each Dilantin— Extended Phenytoin Sodium Capsule, USP—contains 30 mg phenytoin sodium, USP. Also contains lactose, NF; confectioner's sugar, NF; talc, USP; and magnesium stearate, NF. The capsule shell and band contain colloidal silicon dioxide, NF; FD&C red No. 3; gelatin, NF; glyceryl monooleate; sodium lauryl sulfate, NF, citric acid, USP; FD&C blue No. 1; sodium benzoate, NF; titanium dioxide, USP. Product in vivo performance is characterized by a slow and extended rate of absorption with peak blood concentrations expected in 4 to 12 hours as contrasted to Prompt Phenytoin Sodium Capsules, USP with a rapid rate of absorption with peak blood concentration expected in 1% to 3 hours.
What are the precautions when taking extended phenytoin sodium capsules (Dilantin Kapseals)?
Before taking phenytoin, tell your doctor or pharmacist if you are allergic to it; or to other anti-seizure medications (e.g., carbamazepine, ethotoin, phenobarbital, ethosuximide, trimethadione); or if you have any other allergies. This product may contain inactive ingredients, which can cause allergic reactions or other problems. Talk to your pharmacist for more details.
Before using this medication, tell your doctor or pharmacist your medical history, especially of: alcohol use, certain blood conditions (porphyria), diabetes, liver disease, lupus, folate or vitamin B-12 deficiency (megaloblastic anemia).
This drug may make you dizzy or drowsy. Do not drive, use machinery, or do any activity that requires alertness until you are sure you can perform such activities...
Last reviewed on RxList: 5/19/2009
This monograph has been modified to include the generic and brand name in many instances.
Additional Dilantin Kapseals Information
- Dilantin Kapseals Drug Interactions Center: phenytoin sodium extended oral
- Dilantin Kapseals Side Effects Center
- Dilantin Kapseals Overview including Precautions
- Dilantin Kapseals FDA Approved Prescribing Information including Dosage
Dilantin Infatabs - User Reviews
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