Dilantin Kapseals (Extended Phenytoin Sodium Capsules) Drug Information: Description, User Reviews, Drug Side Effects, Interactions

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February 10, 2012

Dilantin Kapseals

Antacids »

What are antacids, and how do they work?

Antacids are a class of drugs used to treat conditions caused by the acid that is produced by the stomach. The stomach naturally secretes an acid called hydrochloric acid that helps to break down proteins. This acid causes the contents of the stomach to be acidic in nature, with a pH level of 2 or 3. (pH levels are a measure of acidity in the stomach: the lower the number, the greater the acidity.) The stomach, duodenum, and esophagus are protected from acid by several protective mechanisms. When there is too much acid or protective mechanisms are inadequate, the lining of the stomach, duodenum or esophagus may become damaged by the acid, giving rise to various gastrointestinal symptoms such as abdominal pain, heartburn (due to gastroesophageal reflux disease or GERD), and other gastro-esophageal symptoms.

Antacids reduce acidity by neutralizing (counteracting) acid, reducing the acidity in the stomac...

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Dilantin Kapseals

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Dilantin® KAPSEALS®
(extended phenytoin sodium) Capsules, USP

DRUG DESCRIPTION

Phenytoin sodium is an antiepileptic drug. Phenytoin sodium is related to the barbiturates in chemical structure, but has a five-membered ring. The chemical name is sodium 5,5-diphenyl-2, 4-imidazolidinedione, having the following structural formula:

Dilantin (Phenytoin Sodium) structural formula illustration

Each Dilantin— Extended Phenytoin Sodium Capsule, USP—contains 30 mg phenytoin sodium, USP. Also contains lactose, NF; confectioner's sugar, NF; talc, USP; and magnesium stearate, NF. The capsule shell and band contain colloidal silicon dioxide, NF; FD&C red No. 3; gelatin, NF; glyceryl monooleate; sodium lauryl sulfate, NF, citric acid, USP; FD&C blue No. 1; sodium benzoate, NF; titanium dioxide, USP. Product in vivo performance is characterized by a slow and extended rate of absorption with peak blood concentrations expected in 4 to 12 hours as contrasted to Prompt Phenytoin Sodium Capsules, USP with a rapid rate of absorption with peak blood concentration expected in 1% to 3 hours.

Last reviewed on RxList: 5/19/2009
This monograph has been modified to include the generic and brand name in many instances.