"Repeated subcutaneous injections of botulinum toxin A (Botox, Allergan) provides analgesic relief to patients with neuropathic pain, a new randomized controlled trial has shown.
The study showed that two series of injections "...
DILAUDID ORAL LIQUID AND DILAUDID TABLETS CONTAIN HYDROMORPHONE, WHICH IS A POTENT SCHEDULE II CONTROLLED OPIOID AGONIST. SCHEDULE II OPIOID AGONISTS, INCLUDING MORPHINE, OXYMORPHONE, OXYCODONE, FENTANYL, AND METHADONE, HAVE THE HIGHEST POTENTIAL FOR ABUSE AND RISK OF PRODUCING RESPIRATORY DEPRESSION. ALCOHOL, OTHER OPIOIDS AND CENTRAL NERVOUS SYSTEM DEPRESSANTS (SEDATIVE-HYPNOTICS) POTENTIATE THE RESPIRATORY DEPRESSANT EFFECTS OF HYDROMORPHONE, INCREASING THE RISK OF RESPIRATORY DEPRESSION THAT MIGHT RESULT IN DEATH.
The chemical name of DILAUDID (hydromorphone hydrochloride) is 4,5α-epoxy-3-hydroxy-17- methylmorphinan-6-one hydrochloride. The structural formula is:
Each 5 mL (1 teaspoon) of DILAUDID ORAL LIQUID contains 5 mg of hydromorphone hydrochloride. In addition, other ingredients include purified water, methylparaben, propylparaben, sucrose, and glycerin. DILAUDID ORAL LIQUID may contain traces of sodium metabisulfite.
Color Coded Tablets (for Oral Administration) Contain:
2 mg hydromorphone hydrochloride (orange tablet) and D&C red #30 Lake dye, D&C yellow #10 Lake dye, lactose, and magnesium stearate. DILAUDID 2 mg TABLET may contain traces of sodium metabisulfite.
4 mg hydromorphone hydrochloride (yellow tablet) and D&C yellow #10 Lake dye, lactose, and magnesium stearate. DILAUDID 4 mg TABLET may contain traces of sodium metabisulfite.
8 mg hydromorphone hydrochloride (white tablet) and lactose anhydrous, and magnesium stearate. DILAUDID 8 mg TABLET may contain traces of sodium metabisulfite.
What are the possible side effects of hydromorphone (Dilaudid, Dilaudid-5, Exalgo)?
Get emergency medical help if you have any of these signs of an allergic reaction: hives; difficulty breathing; swelling of your face, lips, tongue, or throat.
Call your doctor at once if you have a serious side effect such as:
- weak or shallow breathing;
- pounding heartbeats or fluttering in your chest;
- wheezing, chest tightness, trouble breathing;
- seizure (convulsions);
- confusion, severe weakness or drowsiness; or
- feeling like you might pass out.
Less serious side effects are more likely to...
What are the precautions when taking hydromorphone hydrochloride (Dilaudid)?
Before taking hydromorphone, tell your doctor or pharmacist if you are allergic to it; or to hydrocodone; or if you have any other allergies. This product may contain inactive ingredients (such as sulfites), which can cause allergic reactions or other problems. Talk to your pharmacist for more details.
Before using this medication, tell your doctor or pharmacist your medical history, especially of: brain disorders (such as head injury, tumor, seizures), breathing problems (such as asthma, sleep apnea, chronic obstructive pulmonary disease-COPD), kidney disease, liver disease, mental/mood disorders (such as confusion, depression), personal or family history of regular use/abuse of drugs/alcohol, stomach/intestinal problems (such as blockage, constipation, diarrhea due to...
Last reviewed on RxList: 7/16/2015
This monograph has been modified to include the generic and brand name in many instances.
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