"The US Food and Drug Administration (FDA) has approved an extended-release (ER) morphine sulfate C-II (Arymo ER, Egalet Corp) for the management of pain severe enough to require round-the-clock, long-term opioid management for which alte"...
Dilaudid-HP Patient Information including How Should I Take
In this Article
- What is hydromorphone injection (Dilaudid-HP)?
- What are the possible side effects of hydromorphone injection (Dilaudid-HP)?
- What is the most important information I should know about hydromorphone injection (Dilaudid-HP)?
- What should I discuss with my healthcare provider before receiving hydromorphone injection (Dilaudid-HP)?
- How is hydromorphone injection given (Dilaudid-HP)?
- What happens if I miss a dose (Dilaudid-HP)?
- What happens if I overdose (Dilaudid-HP)?
- What should I avoid while receiving hydromorphone injection (Dilaudid-HP)?
- What other drugs will affect hydromorphone injection (Dilaudid-HP)?
- Where can I get more information?
What should I discuss with my healthcare provider before receiving hydromorphone injection (Dilaudid-HP)?
You should not use this medication if you have ever had an allergic reaction to a narcotic medicine (examples include codeine, methadone, morphine, Lortab, OxyContin, Percocet, Vicodin, and many others).
You should also not use hydromorphone injection if you have:
- a bowel obstruction called paralytic ileus; or
- if you are having an asthma attack.
Do not use hydromorphone if you have used an MAO inhibitor such as furazolidone (Furoxone), isocarboxazid (Marplan), phenelzine (Nardil), rasagiline (Azilect), selegiline (Eldepryl, Emsam, Zelapar), or tranylcypromine (Parnate) in the last 14 days. A dangerous drug interaction could occur, leading to serious side effects.
You may not be able to use hydromorphone injection unless you are already being treated with a similar opioid pain medicine and your body is tolerant to it. Opioid medicines include fentanyl (Actiq, Duragesic), methadone (Methadose, Dolophine), morphine (Kadian, MS Contin, Oramorph), oxycodone (Oxycontin), oxymorphone (Opana), and many others. Talk with your doctor if you are not sure you are opioid-tolerant.
To make sure you can safely use hydromorphone, tell your doctor if you have any of these other conditions:
- asthma, COPD, sleep apnea, or other breathing disorders;
- sulfite allergy;
- liver or kidney disease;
- underactive thyroid;
- curvature of the spine;
- a history of head injury or brain tumor;
- epilepsy or other seizure disorder;
- low blood pressure;
- gallbladder disease or pancreatitis;
- Addison's disease or other adrenal gland disorders;
- enlarged prostate, urination problems;
- mental illness;
- a history of alcoholism or drug addiction; or
- if you have recently used alcohol, sedatives, tranquilizers, or other narcotic medications.
Hydromorphone may be habit forming and should be used only by the person for whom it was prescribed. Never share hydromorphone with another person, especially someone with a history of drug abuse or addiction. Keep the medication in a place where others cannot get to it.
FDA pregnancy category C. It is not known whether hydromorphone will harm an unborn baby. Hydromorphone may cause addiction or withdrawal symptoms in a newborn if the mother uses the medication during pregnancy. Tell your doctor if you are pregnant or plan to become pregnant while using hydromorphone.
Hydromorphone can pass into breast milk and may harm a nursing baby. You should not breast-feed while you are using hydromorphone.
Serious side effects may be more likely in older adults and those who are ill or debilitated.
How is hydromorphone injection given (Dilaudid-HP)?
Use exactly as prescribed. Never use hydromorphone in larger amounts, or for longer than recommended by your doctor. Follow the directions on your prescription label. Tell your doctor if the medicine seems to stop working as well in relieving your pain.
Hydromorphone is injected under the skin or into a muscle, or into a vein through an IV. You may be shown how to use injections at home. Do not self-inject this medicine if you do not fully understand how to give the injection and properly dispose of used needles, IV tubing, and other items used to inject the medicine.
Hydromorphone injected into a vein must be given slowly, and the IV infusion should take at least 2 to 3 minutes to complete.
Your doctor may occasionally change your dose to make sure you get the best results. Your dose needs may be different if you have recently used an opioid pain medicine and your body is tolerant to it.
You may need to mix hydromorphone with a liquid (diluent) before using it. If you are using the injections at home, be sure you understand how to properly mix and store the medicine.
Do not use hydromorphone if it has changed colors or has particles in it. Call your doctor for a new prescription.
If you need surgery, tell the surgeon ahead of time that you are using hydromorphone. You may need to stop using the medicine for a short time.
Do not stop using hydromorphone suddenly, or you could have unpleasant withdrawal symptoms. Ask your doctor how to avoid withdrawal symptoms when you stop using hydromorphone.
Store at room temperature away from moisture, heat, and light.
Keep track of the amount of medicine used from each new bottle. Hydromorphone is a drug of abuse and you should be aware if anyone is using your medicine improperly or without a prescription. After you have stopped using this medication, flush any unused medicine down the toilet.
Additional Dilaudid-HP Information
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Report Problems to the Food and Drug Administration
You are encouraged to report negative side effects of prescription drugs to the FDA. Visit the FDA MedWatch website or call 1-800-FDA-1088.
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