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Dilaudid-HP

Last reviewed on RxList: 7/16/2015
Dilaudid-HP Side Effects Center

Last reviewed on RxList 01/19/2017

Dilaudid-HP (hydromorphone hydrochloride) Injection is a narcotic pain reliever used to treat moderate to severe pain. Dilaudid-HP is available in generic form. Common side effects of Dilaudid-HP include:

  • nausea,
  • vomiting,
  • constipation,
  • diarrhea,
  • stomach pain,
  • lightheadedness,
  • dizziness,
  • drowsiness,
  • blurred vision,
  • double vision,
  • flushing (warmth, redness, tingly feeling),
  • dry mouth,
  • sweating,
  • itching,
  • sleep problems (insomnia),
  • strange dreams, or
  • injection site reactions (pain, redness, or swelling).

Tell your doctor if you have unlikely but serious side effects of Dilaudid-HP including:

Dosage of Dilaudid-HP is individualized and determined based on the patient's age, general condition, medical status, type and severity of pain, risk factors for abuse or addiction, and other factors. Dilaudid-HP may interact with other narcotic pain medications, sedatives, tranquilizers, muscle relaxers, medicines that make you sleepy or slow breathing, pentazocine, nalbuphine, butorphanol, or buprenorphine. Tell your doctor all medications you use. During pregnancy, Dilaudid-HP should be used only when prescribed. Using it near the expected delivery date is not recommended because of possible harm to the fetus. Infants born to mothers who have used this medication may have breathing problems or withdrawal symptoms such as irritability, abnormal/persistent crying, vomiting, or diarrhea. Tell your doctor if you notice these symptoms in your newborn. This medication may pass into breast milk. Consult your doctor before breastfeeding. Dilaudid-HP may be habit-forming. Do not stop using Dilaudid-HP suddenly, or you could have withdrawal symptoms.

Our Dilaudid-HP (hydromorphone hydrochloride) Side Effects Drug Center provides a comprehensive view of available drug information on the potential side effects when taking this medication.

This is not a complete list of side effects and others may occur. Call your doctor for medical advice about side effects. You may report side effects to FDA at 1-800-FDA-1088.

Dilaudid-HP Consumer Information

Get emergency medical help if you have any of these signs of an allergic reaction: hives; difficulty breathing; swelling of your face, lips, tongue, or throat.

Call your doctor at once if you have a serious side effect such as:

  • weak or shallow breathing, feeling like you might pass out.;
  • pounding heartbeats or fluttering in your chest;
  • wheezing, chest tightness, trouble breathing;
  • seizure (convulsions); or
  • confusion, severe weakness or drowsiness.

Less serious side effects may include:

  • blurred vision, double vision;
  • flushing (warmth, redness, or tingly feeling);
  • nausea, vomiting, constipation, diarrhea, stomach pain;
  • dizziness, drowsiness;
  • pain where the injection was given;
  • dry mouth;
  • sweating, itching; or;
  • sleep problems (insomnia), or strange dreams.

This is not a complete list of side effects and others may occur. Call your doctor for medical advice about side effects. You may report side effects to FDA at 1-800-FDA-1088.

Read the entire detailed patient monograph for Dilaudid-HP (Hydromorphone Hydrochloride Injection)

Dilaudid-HP Professional Information

SIDE EFFECTS

Because clinical trials are conducted under widely varying conditions, adverse reaction rates observed in the clinical trials of a drug cannot be directly compared to rates in the clinical trials of another drug and may not reflect the rates observed in clinical practice.

Serious adverse reactions associated with DILAUDID INJECTION and DILAUDID-HP INJECTION include respiratory depression and apnea and, to a lesser degree, circulatory depression, respiratory arrest, shock, and cardiac arrest.

The following serious adverse reactions described elsewhere in the labeling include:

The most common adverse effects are lightheadedness, dizziness, sedation, nausea, vomiting, sweating, flushing, dysphoria, euphoria, dry mouth, and pruritus. These effects seem to be more prominent in ambulatory patients and in those not experiencing severe pain.

Less Frequently Observed Adverse Reactions

Cardiac disorders: tachycardia, bradycardia, palpitations

Eye disorders: vision blurred, diplopia, miosis, visual impairment

Gastrointestinal disorders: constipation, ileus, diarrhea, abdominal pain

General disorders and administration site conditions: weakness, feeling abnormal, chills, injection site urticaria

Hepatobiliary disorders: biliary colic

Metabolism and nutrition disorders: decreased appetite

Musculoskeletal and connective tissue disorders: muscle rigidity

Nervous system disorders: headache, tremor, paraesthesia, nystagmus, increased intracranial pressure, syncope, taste alteration, involuntary muscle contractions, presyncope

Psychiatric disorders: agitation, mood altered, nervousness, anxiety, depression, hallucination, disorientation, insomnia, abnormal dreams

Renal and urinary disorders: urinary retention, urinary hesitation, antidiuretic effects

Respiratory, thoracic, and mediastinal disorders: bronchospasm, laryngospasm

Skin and subcutaneous tissue disorders: injection site pain, urticaria, rash, hyperhidrosis

Vascular disorders: flushing, hypotension, hypertension

Postmarketing Experience

The following adverse reactions have been identified during post-approval use of hydromorphone. Because these events are reported voluntarily from a population of uncertain size, it is not always possible to reliably estimate their frequency or establish a causal relationship to drug exposure: anaphylactic reactions, confusional state, convulsions, drowsiness, dyskinesia, dyspnea, erectile dysfunction, fatigue, hepatic enzymes increased, hyperalgesia, hypersensitivity reaction, injection site reactions, lethargy, myoclonus, oropharyngeal swelling, peripheral edema, and somnolence.

Read the entire FDA prescribing information for Dilaudid-HP (Hydromorphone Hydrochloride Injection)

Related Resources for Dilaudid-HP

Read the Dilaudid-HP User Reviews »

© Dilaudid-HP Patient Information is supplied by Cerner Multum, Inc. and Dilaudid-HP Consumer information is supplied by First Databank, Inc., used under license and subject to their respective copyrights.

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