Diprolene AF (Betamethasone) Drug Information: Description, User Reviews, Drug Side Effects, Interactions

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February 8, 2012

Diprolene AF

Poison Ivy »

Poison ivy, oak, and sumac facts

Many people are susceptible to the rashes of poison ivy, oak, and sumac.

The sap oil, called urushiol, causes the skin rash.

Poison ivy is not contagious.

Washing the oily sap from the skin with water and soap immediately can help prevent the rash.

Avoiding direct contact with the plants can prevent the rash.

What causes the rash? How do I identify poison ivy, oak, and sumac?

Poison ivy is a common cause of contact dermatitis, an allergic reaction to something that comes in direct contact with the skin. Allergic contact dermatitis as a response to plants is sometimes referred to as allergic phytodermatitis. This condition can be quite unpleasant but does not typically pose serious health risks. Prevention of the condition is best.

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Read the Poison Ivy article »

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Diprolene AF User Reviews >>

Diprolene AF

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DIPROLENE® AF
(augmented betamethasone dipropionate)* Cream 0.05%
(potency expressed as betamethasone)

*Vehicle augments the penetration of the steroid.

For Dermatologic Use Only - Not for Ophthalmic Use

DRUG DESCRIPTION

DIPROLENE® AF Cream 0.05% contains betamethasone dipropionate, USP, a synthetic adrenocorticosteroid, for dermatologic use in an emollient base. Betamethasone, an analog of prednisolone, has a high degree of corticosteroid activity and a slight degree of mineralocorticoid activity. Betamethasone dipropionate is the 17, 21-dipropionate ester of betamethasone.

Chemically, betamethasone dipropionate is 9-fluoro-11β,17,21-trihydroxy-16β- methylpregna-1,4-diene-3,20-dione 17,21-dipropionate, with the empirical formula C₂₈H₃₇FO₇, a molecular weight of 504.6, and the following structural formula:

DIPROLENE® AF (betamethasone dipropionate) Structural Formula Illustration

Betamethasone dipropionate is a white to creamy white, odorless crystalline powder, insoluble in water.

Each gram of DIPROLENE AF Cream 0.05% contains: 0.643 mg betamethasone dipropionate, USP (equivalent to 0.5 mg betamethasone) in an emollient cream base of purified water, USP; chlorocresol; propylene glycol, USP; white petrolatum, USP; white wax, NF; cyclomethicone; sorbitol solution, USP; glyceryl oleate/propylene glycol; ceteareth-30; carbomer 940, NF; and sodium hydroxide R.

What are the precautions when taking betamethasone (Diprolene AF)?

Before using betamethasone, tell your doctor or pharmacist if you are allergic to it; or to other corticosteroids (e.g., hydrocortisone, prednisone); or if you have any other allergies. This product may contain inactive ingredients, which can cause allergic reactions or other problems. Talk to your pharmacist for more details.

Before using this medication, tell your doctor or pharmacist your medical history, especially of: poor blood circulation, immune system problems, certain skin conditions if using the gel (rosacea, perioral dermatitis).

Do not use if there is an infection or sore present in the area to be treated.

Rarely, using corticosteroid medications for a long time or over large areas of skin can make it more difficult for your body to respond to physical...

Read All Potential Precautions of Diprolene AF »

Last reviewed on RxList: 10/14/2008
This monograph has been modified to include the generic and brand name in many instances.