"The U.S. Food and Drug Administration today approved Siliq (brodalumab) to treat adults with moderate-to-severe plaque psoriasis. Siliq is administered as an injection.
Siliq is intended for patients who are candidates for systemic therapy "...
DOSAGE AND ADMINISTRATION
Apply a few drops of DIPROLENE Lotion to the affected skin areas once or twice daily and massage lightly until the lotion disappears.
Therapy should be discontinued when control is achieved. If no improvement is seen within 2 weeks, reassessment of diagnosis may be necessary. DIPROLENE Lotion is a super-high-potency topical corticosteroid. Treatment with DIPROLENE Lotion should be limited to 2 consecutive weeks and amounts should not exceed 50 mL per week because of the potential for the drug to suppress the hypothalamic-pituitary-adrenal (HPA) axis.
DIPROLENE Lotion should not be used with occlusive dressings unless directed by a physician.
DIPROLENE Lotion is for topical use only. It is not for oral, ophthalmic, or intravaginal use.
Dosage Forms And Strengths
Lotion, 0.05%. Each gram of DIPROLENE Lotion, 0.05% contains 0.643 mg betamethasone dipropionate (equivalent to 0.5 mg betamethasone) in a colorless, clear to translucent lotion.
Storage And Handling
DIPROLENE Lotion 0.05% is a colorless, clear to translucent lotion supplied in 30-mL (29 g) (NDC 0085-0962-01) and 60-mL (58 g) (NDC 0085-0962-02) plastic bottles.
Store at 25°C (77°F); excursions permitted to 15-30°C (59-86°F) [see USP Controlled Room Temperature].
Manufactured by: Bayer Inc. Pointe Claire, Quebec H9R 1B4, Canada.. For: Merck Sharp & Dohme Corp., a subsidiary of Merck & Co., USA. For patent information: www.merck.com/product/patent/home.htmlThis monograph has been modified to include the generic and brand name in many instances.
Last reviewed on RxList: 8/2/2016
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