Diphtheria and Tetanus (Diphtheria and Tetanus Toxoids) Drug Information: Overdosage and Contraindications

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May 27, 2012

Diptheria and Tetanus

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Tetanus facts

Tetanus is frequently a fatal infectious disease.
Tetanus is caused by a type of bacteria (Clostridium tetani).
The tetanus bacteria often enter the body through a puncture wound, which can be caused by nails, splinters, insect bites, burns, any skin break, and injection-drug sites.
All children and adults should be immunized against tetanus by receiving vaccinations.
A tetanus booster is needed every 10 years after primary immunization or after a puncture or other skin wound which could provide the tetanus bacteria an opportunity to enter the body.

What is tetanus?

Tetanus is an acute, often-fatal disease of the nervous system that is caused by nerve toxins produced by the bacterium Clostridium tetani. This bacterium is found throughout the world in the soil and in animal and human intestines.

Where do tetanus bacteria ...

Read the Tetanus article »

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Diphtheria and Tetanus

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OVERDOSE

No information provided..

CONTRAINDICATIONS

HYPERSENSITIVITY TO ANY COMPONENT OF THE VACCINE,INCLUDING THIMEROSAL, A MERCURY DERIVATIVE,IS A CONTRAINDICATION FOR FURTHER USE OF THIS VACCINE.

It is a contraindication to use this or any other related vaccine after an immediate anaphylactic reaction associated with a previous dose.

A history of systemic allergic or neurologic reactions following a previous dose of DT is an absolute contraindication for further use.²

If a contraindication to using tetanus toxoid-containing preparations exists in a person who has not completed a primary immunizing course of tetanus toxoid and other than a clean, minor wound is sustained, only passive immunization should be given using TIG (Human).²

Immunization should be deferred during the course of an acute illness. Vaccination of infants and children with severe, febrile illness should generally be deferred until these persons have recovered. However, the presence of minor illnesses such as mild upper respiratory infections with or without low grade fever should not preclude vaccination.²

Elective immunization procedures should be deferred during an outbreak of poliomyelitis.⁸

REFERENCES

2. Recommendations of the Advisory Committee on Immunization Practices (ACIP).Diphtheria, Tetanus, and Pertussis: Recommendations for vaccine use and other preventive measures. MMWR 40:No.RR-10,1991

8. Wilson GS. The Hazards of Immunization. Provocation poliomyelitis.270-274,1967

Last reviewed on RxList: 6/8/2006
This monograph has been modified to include the generic and brand name in many instances.