Disalcid (Salsalate) Drug Information: Overdosage and Contraindications

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May 27, 2012

Disalcid

Osteoarthritis »

Osteoarthritis facts

Osteoarthritis is a joint inflammation that results from cartilage degeneration.
Osteoarthritis can be caused by aging, heredity, and injury from trauma or disease.
The most common symptom of osteoarthritis is pain in the affected joint(s) after repetitive use.
There is no blood test for the diagnosis of osteoarthritis.
The goal of treatment in osteoarthritis is to reduce joint pain and inflammation while improving and maintaining joint function.

What is osteoarthritis?

Osteoarthritis is a form of arthritis that features the breakdown and eventual loss of the cartilage of one or more joints. Cartilage is a protein substance that serves as a "cushion" between the bones of the joints. Among the over 100 different types of arthritis conditions, osteoarthritis is the most common, affecting over 25 million people in the United Stat...

Read the Osteoarthritis article »

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Disalcid

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Please Note: This Brand Name drug is no longer available in the US.
(Generic versions may still be available.)

OVERDOSE

Death has followed ingestion of 10 to 30 g of salicylates in adults, but much larger amounts have been ingested without fatal outcome.

Symptoms

The usual symptoms of salicylism - tinnitus, vertigo, headache, confusion, drowsiness, sweating, hyperventilation, vomiting and diarrhea - will occur. More severe intoxication will lead to disruption of electrolyte balance and blood pH, and hyperthermia and dehydration.

Treatment

Further absorption of DISALCID (salsalate) from the G.I. tract should be prevented by emesis (syrup of ipecac) and if necessary, by gastric lavage.

Fluid and electrolyte imbalance should be corrected by the administration of appropriate I.V. therapy. Adequate renal function should be maintained. Hemodialysis or peritoneal dialysis may be required in extreme cases.