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Diuretics (cont.)

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For what conditions are diuretics used?

Diuretics are used with other types of medications (adjunctive therapy) in edema associated with congestive heart failure (CHF), cirrhosis of the liver, and corticosteroid and estrogen therapy.

Diuretics also are useful in edema caused by renal dysfunction (for example, nephrotic syndrome, acute glomerulonephritis, and chronic renal failure). Diuretics are used to lower urinary calcium excretion, making them useful in preventing calcium-containing kidney stones.

Diuretics are used as the sole therapeutic agents to treat hypertension. Diuretics can also be used in combination with other antihypertensive drugs to treat more severe forms of hypertension.

Diuretics (specifically the carbonic anhydrase inhibitors) are used as adjunctive treatment of chronic simple (open-angle) glaucoma and secondary glaucoma

Thiazide diuretics have off–label (non-FDA-approved) uses for osteoporosis in postmenopausal women. They can be given alone or in combination with calcium or estrogen. Thiazide diuretics also have off-label uses for treating diabetes insipidus.



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