Dolobid (Diflunisal) Patient Information: How Should I Take the Drug at RxList

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May 27, 2012

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Ankylosing Spondylitis »

Ankylosing spondylitis facts

Ankylosing spondylitis belongs to a group of arthritis conditions which tend to cause chronic inflammation of the spine (spondyloarthropathies).
Ankylosing spondylitis affects males two to three times more commonly than females.
Ankylosing spondylitis is a cause of back pain in adolescents and young adults.
The tendency to develop ankylosing spondylitis is genetically inherited.
The HLA-B27 gene can be detected in the blood of most patients with ankylosing spondylitis.
Ankylosing spondylitis can also affect the eyes, heart, lungs, and occasionally the kidneys.
The optimal treatment of ankylosing spondylitis involves medications that reduce inflammation or suppress immunity, physical therapy, and exercise.

What is ankylosing spondylitis?

Ankylosing spondylitis is a form of chronic inflammat...

Read the Ankylosing Spondylitis article »

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Dolobid Patient Information including How Should I Take

What should I discuss with my healthcare provider before taking diflunisal (Dolobid)?

Taking an NSAID can increase your risk of life-threatening heart or circulation problems, including heart attack or stroke. This risk will increase the longer you use an NSAID. Do not use this medicine just before or after having heart bypass surgery (also called coronary artery bypass graft, or CABG).

NSAIDs can also increase your risk of serious effects on the stomach or intestines, including bleeding or perforation (forming of a hole). These conditions can be fatal and gastrointestinal effects can occur without warning at any time while you are taking an NSAID. Older adults may have an even greater risk of these serious gastrointestinal side effects.

Do not use this medication if you are allergic to diflunisal, or if you have a history of allergic reaction to aspirin or other NSAIDs.

If you have any of these other conditions, you may need a dose adjustment or special tests to safely take diflunisal:

a history of heart attack, stroke, or blood clot;
heart disease, congestive heart failure, high blood pressure;
a history of stomach ulcers or bleeding;
liver or kidney disease;
asthma;
polyps in your nose;
a bleeding or blood clotting disorder; or
if you smoke.

FDA pregnancy category C. It is not known whether diflunisal is harmful to an unborn baby. Tell your doctor if you are pregnant or plan to become pregnant during treatment. Taking diflunisal during the last 3 months of pregnancy may result in birth defects. Do not take diflunisal during pregnancy unless your doctor has told you to.

Diflunisal can pass into breast milk and could cause harm to a nursing baby. Do not use this medication without telling your doctor if you are breast-feeding a baby.

Do not give this medicine to a child younger than 12 years old without the advice of a doctor.

How should I take diflunisal (Dolobid)?

Take this medication exactly as it was prescribed for you. Do not take the medication in larger amounts, or take it for longer than recommended by your doctor. Follow the directions on your prescription label.

Take this medicine with a full glass (8 ounces) of water.

Take diflunisal with food or milk to lessen stomach upset.

If you take diflunisal for a long period of time, your doctor may want to check you on a regular basis to make sure this medication is not causing harmful effects. Do not miss any scheduled visits to your doctor.

This medication can cause you to have unusual results with certain medical tests. Tell any doctor who treats you that you are using diflunisal.

Store diflunisal at room temperature away from moisture and heat.

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