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Donnatal

What is irritable bowel syndrome (IBS)?

Irritable bowel syndrome (IBS) is one of the most common ailments of the bowel (intestines) and affects an estimated 15% of people in the US. The term, irritable bowel, is not a particularly accurate one since it implies that the bowel is responding irritably to normal stimuli, and this may or may not be the case. The several terms used for IBS, including spastic colon, spastic colitis, and mucous colitis, attest to the difficulty of getting a descriptive handle on the ailment. Moreover, each of the other names is itself as problematic as the term IBS.

IBS is best described as a functional disease. The concept of functional disease is particularly useful when discussing diseases of the gastrointestinal tract. The concept applies to the muscular organs of the gastrointestinal tract; the esophagus, stomach, small intestine, gallbladder, and colon. What is meant by the term, functional, is that either th...

Donnatal Extentabs

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Donnatal Drug Center

Medical Editor: John P. Cunha, DO, FACOEP

Donnatal (belladonna alkaloids, phenobarbital) is used to treat abdominal pain, bloating and cramps in patients with irritable bowel syndrome. It is also used to treat acute inflammation of the stomach and intestines (gastroenteritis) to reduce pain and diarrhea, and in patients with duodenal ulcer. Donnatal contains belladonna alkaloids (hyoscyamine, atropine, and scopolamine) that belong to the anticholinergic/antispasmodic class of drugs, and phenobarbital that belongs to the barbiturate sedatives class of drugs. This medication is available in generic form. Common side effects include dizziness, drowsiness, weakness, blurred vision, dry eyes, dry mouth, nausea, constipation, and abdominal bloating.

The dosage of Donnatal is adjusted to individual patients for symptomatic control with minimum adverse reactions. The usual dose is one tablet every 8 or 12 hours as prescribed. Products that may interact with Donnatal include blood thinners, ketoconazole, MAO inhibitors, bronchodilators, bladder or urinary medications or irritable bowel medications. Hormonal birth control products (pills, patch, ring) may not be effective if taken with Donnatal. Discuss all medications you are taking with your doctor. Donnatal is not recommended for use during pregnancy. It may harm a fetus. Consult your doctor. This medication passes into breast milk and may have undesirable effects on a nursing infant. Consult your doctor before breast-feeding. Donnatal may cause withdrawal symptoms (anxiety, muscle twitching, shakiness, dizziness, worsening weakness, nausea, vomiting) if you suddenly stop using it. Withdrawal from phenobarbital can be severe and include seizures or death.

Our Donnatal Drug Center provides a comprehensive view of available drug information as well as related drugs, user reviews, supplements, and diseases and conditions articles.

What is Prescribing information?

The FDA package insert formatted in easy-to-find categories for health professionals and clinicians.

Donnatal Prescribing Information: Indications & Dosage

Based on a review of this drug by the National Academy of Sciences - National Research Council and/or other information, FDA has classified the following indications as "possibly" effective:

For use as adjunctive therapy in the treatment of irritable bowel syndrome (irritable colon, spastic colon, mucous colitis) and acute enterocolitis.

May also be useful as adjunctive therapy in the treatment of duodenal ulcer. IT HAS NOT BEEN SHOWN CONCLUSIVELY WHETHER ANTICHOLINERGIC/ANTISPASMODIC DRUGS AID IN THE HEALING OF A DUODENAL ULCER, DECREASE THE RATE OF REC...

Read the complete drug monograph for Donnatal »

What is Patient information?

Easy-to-read and understand detailed drug information and pill images for the patient or caregiver from Cerner Multum.

Donnatal Patient Information: Side Effects

Get emergency medical help if you have any of these signs of an allergic reaction: hives; difficulty breathing; swelling of your face, lips, tongue, or throat.

Stop using this medication and call your doctor at once if you have any of these serious side effects:

  • diarrhea;
  • painful or difficult urination;
  • fast or pounding heartbeats;
  • blurred vision with eye pain, or seeing halos around lights;
  • feeling like you might pass out; or
  • mouth sores, red or bleeding gums, or tooth decay (with long-term use).
  • /...

Read the complete patient information for Donnatal »

What is Consumer information?

A concise overview of the drug for the patient or caregiver from First DataBank.

Donnatal Consumer Information: Uses

This product contains several medications: belladonna alkaloids (made up of the drugs hyoscyamine, atropine, and scopolamine) and phenobarbital. Belladonna alkaloids help to reduce the symptoms of stomach and intestinal cramping. They work by slowing the natural movements of the gut and by relaxing the muscles in the stomach and intestines. Belladonna alkaloids belong to a class of drugs known as anticholinergics/antispasmodics. Phenobarbital helps to reduce anxiety. It acts on the brain to produce a calming effect. Phenobarbital belongs to a class of drugs known as barbiturate sedatives.

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Read the complete consumer information for Donnatal »

What is Donnatal Consumer Information?

Warnings - Uses - How to Use - Side Effects - Precautions - Drug Interactions and More

Donnatal Extentabs - User Reviews

Donnatal Extentabs User Reviews

Now you can gain knowledge and insight about a drug treatment with Patient Discussions.

Here is a collection of user reviews for the medication Donnatal Extentabs sorted by most helpful. Patient Discussions FAQs

Report Problems to the Food and Drug Administration

 

You are encouraged to report negative side effects of prescription drugs to the FDA. Visit the FDA MedWatch website or call 1-800-FDA-1088.


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