May 24, 2017
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"The U.S. Food and Drug Administration today approved Viberzi (eluxadoline) and Xifaxan (rifaximin), two new treatments, manufactured by two different companies, for irritable bowel syndrome with diarrhea (IBS-D) in adult men and women.



Donnatal Extentabs

Donnatal Extentabs®
(belladonna alkaoids, phenobarbital)


Each Donnatal Extentabs® (belladonna alkaloids, phenobarbital) tablet contains:

Phenobarbital, USP (3/4 gr.) ................................ 48.6 mg
Hyoscyamine Sulfate, USP ................................... 0.3111 mg
Atropine Sulfate, USP ............................................ 0.0582 mg
Scopolamine Hydrobromide, USP ...................... 0.0195 mg

Each Donnatal Extentabs® (belladonna alkaloids, phenobarbital) tablet contains the equivalent of three Donnatal® tablets. Extentabs® are designed to release the ingredients gradually to provide effects for up to twelve (12) hours.

In addition, each tablet contains the following inactive ingredients: Anhydrous Lactose, Calcium Sulfate Granular, Colloidal Silicon Dioxide, Dibasic Calcium Phosphate, Lactose Monohydrate, Magnesium Stearate, and Stearic Acid. Film Coating and Polishing Solution contains: D&C Yellow #10 Aluminum Lake, FD&C Blue #1 Aluminum Lake, Hydroxypropyl Methylcellulose, Polydextrose, Polyethylene Glycol, Titanium Dioxide, and Triacetin. The printing ink contains Titanium Dioxide.

What are the possible side effects of belladonna alkaloids and phenobarbital (Bellatal, Donnatal, D-Tal)?

Get emergency medical help if you have any of these signs of an allergic reaction: hives; difficulty breathing; swelling of your face, lips, tongue, or throat.

Stop using this medication and call your doctor at once if you have any of these serious side effects:

  • diarrhea;
  • painful or difficult urination;
  • fast or pounding heartbeats;
  • blurred vision with eye pain, or seeing halos around lights;
  • feeling like you might pass out; or
  • mouth sores, red or bleeding gums, or tooth decay (with...

Read All Potential Side Effects and See Pictures of Donnatal Extentabs »

What are the precautions when taking belladonna alkaloids, phenobarbital (Donnatal Extentabs)?

Before taking this medication, tell your doctor or pharmacist if you are allergic to hyoscyamine, atropine, scopolamine, or phenobarbital; or to primidone; or if you have any other allergies. This product may contain inactive ingredients, which can cause allergic reactions or other problems. Talk to your pharmacist for more details.

Before using this medication, tell your doctor or pharmacist your medical history, especially of: personal or family history of glaucoma (angle-closure type), enlarged prostate, problems with urination due to a blocked urinary tract, other stomach/intestinal problems (such as slow gut, blockage, ulcerative colitis, infection, little/no stomach acid, ileostomy/colostomy patients with diarrhea), overactive thyroid, heart problems (such as coronary...

Read All Potential Precautions of Donnatal Extentabs »

Last reviewed on RxList: 2/3/2017
This monograph has been modified to include the generic and brand name in many instances.

Donnatal Extentabs - User Reviews

Donnatal Extentabs User Reviews

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Here is a collection of user reviews for the medication Donnatal Extentabs sorted by most helpful. Patient Discussions FAQs

Report Problems to the Food and Drug Administration


You are encouraged to report negative side effects of prescription drugs to the FDA. Visit the FDA MedWatch website or call 1-800-FDA-1088.

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