"The cystic fibrosis (CF) drug Orkambi (Vertex Pharmaceuticals) has received a green light from the European Medicines Agency (EMA) Committee for Medicinal Products for Human Use (CHMP).
Orkambi is a fixed-dose oral combination "...
(Generic versions may still be available.)
|In order to reduce the high incidence of adverse reactions, it is necessary to individualize the therapy and to gradually increase the dosage to the desired therapeutic level.|
Larodopa is available as tablets containing 0.1 g, 0.25 g or 0.5 g levodopa. Each tablet also contains corn starch, magnesium stearate, microcrystalline cellulose, povidone, talc and D&C Red No.7 lake dye.
Chemically, levodopa is (-)-3-(3,4-dihydroxy-phenyl)-L-alanine. It is a colorless, crystalline compound, slightly soluble in water and insoluble in alcohol, with a molecular weight of 197.2.
Last reviewed on RxList: 12/8/2004
This monograph has been modified to include the generic and brand name in many instances.
Additional Dopar Information
- Dopar Drug Interactions Center: levodopa oral
- Dopar Side Effects Center
- Dopar FDA Approved Prescribing Information including Dosage
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