Doral (Quazepam Tablets) Drug Information: Description, User Reviews, Drug Side Effects, Interactions

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February 10, 2012

Doral

Insomnia »

What is insomnia?

Insomnia is defined as difficulty initiating or maintaining sleep, or both, despite adequate opportunity and time to sleep, leading to impaired daytime functioning. Insomnia may be due to poor quality or quantity of sleep.

Insomnia is very common and occurs in 30% to 50% of the general population. Approximately 10% of the population may suffer from chronic (long-standing) insomnia.

Insomnia affects people of all ages including children, although it is more common in adults and its frequency increases with age. In general, women are affected more frequently than men.

Insomnia may be divided into three classes based on the duration of symptoms.

Insomnia lasting one week or less may be termed transient insomnia;
short-term insomnia lasts more than one week but resolves in less than three weeks; and
long-term or chronic insomnia lasts more than three we...

Read the Insomnia article »

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DORAL®
(quazepam) Tablets

DRUG DESCRIPTION

DORAL® (brand of quazepam) Tablets contain quazepam, a trifluoroethyl benzodiazepine hypnotic agent, having the chemical name 7-chloro-5- (o-fluoro-phenyl)-1,3-dihydro-1-(2,2,2-trifluoroethyl)-2H1,4-benzodiazepine-2-thione and the following structural formula:

DORAL ( quazepam) Structural Formula Illustration

Quazepam has the empirical formula C₁₇H₁₁CIF₄N₂S, and a molecular weight of 386.8. It is a white crystalline compound, soluble in ethanol and insoluble in water. Each DORAL® Tablet contains either 7.5 or 15 mg of quazepam. The inactive ingredients for DORAL® (quazepam tablets) Tablets 7.5 or 15 mg include cellulose, corn starch, FD&C Yellow No. 6 Al Lake, lactose, magnesium stearate, silicon dioxide, and sodium lauryl sulfate.

What are the possible side effects of quazepam (Doral)?

Quazepam may cause a severe allergic reaction. Stop taking quazepam and get emergency medical help if you have any of these signs of an allergic reaction: hives; difficulty breathing; swelling of your face, lips, tongue, or throat.

Stop using quazepam and call your doctor at once if you have a serious side effect such as:

worsening insomnia;
confusion, anxiety, slurred speech, unusual thoughts or behavior;
hallucinations, agitation, aggression;
weak or shallow breathing;
fast or...

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What are the precautions when taking quazepam tablets (Doral)?

Before taking quazepam, tell your doctor or pharmacist if you are allergic to it; or to other benzodiazepines (e.g., lorazepam, diazepam); or if you have any other allergies. This product may contain inactive ingredients, which can cause allergic reactions or other problems. Talk to your pharmacist for more details.

Before using this medication, tell your doctor or pharmacist your medical history, especially of: liver disease, kidney disease, mental/mood problems (e.g., depression, panic disorder), lung problems (e.g., pulmonary insufficiency, sleep apnea), seizures, personal or family history of regular use/abuse of drugs/alcohol/other substances.

This drug may make you dizzy or drowsy or cause temporary blurred vision. Do not drive, use machinery, or do any activity that...

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Last reviewed on RxList: 4/30/2010
This monograph has been modified to include the generic and brand name in many instances.