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McKee, a 72-year-old grandmother of four from Bethpage, Tenn., was one of nearly 14,000 people who found out this fall that they'd been exposed to tainted medications made by "...
In the event of overdose, DORIBAX® should be discontinued and general supportive treatment given.
Doripenem can be removed by hemodialysis. In subjects with end-stage renal disease administered DORIBAX® 500 mg, the mean total recovery of doripenem and doripenemM1 in the dialysate following a 4-hour hemodialysis session was 259 mg (52% of the dose). However, no information is available on the use of hemodialysis to treat overdosage. [see CLINICAL PHARMACOLOGY]
DORIBAX® is contraindicated in patients with known serious hypersensitivity to doripenem or to other drugs in the same class or in patients who have demonstrated anaphylactic reactions to beta-lactams.This monograph has been modified to include the generic and brand name in many instances.
Last reviewed on RxList: 8/27/2015
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