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Dostinex

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Dostinex

DOSTINEX®
(cabergoline) Tablets

DRUG DESCRIPTION

DOSTINEX Tablets contain cabergoline, a dopamine receptor agonist. The chemical name for cabergoline is 1-[(6-allylergolin-8-yl)-carbonyl]-1-[3-(dimethylamino) propyl]-3-ethylurea. Its empirical formula is C26H37N5O2, and its molecular weight is 451.62. The structural formula is as follows:

DOSTINEX® (cabergoline) Structural Formula Illustration

Cabergoline is a white powder soluble in ethyl alcohol, chloroform, and N, Ndimethylformamide (DMF); slightly soluble in 0.1N hydrochloric acid; very slightly soluble in n-hexane; and insoluble in water.

DOSTINEX Tablets, for oral administration, contain 0.5 mg of cabergoline. Inactive ingredients consist of leucine, USP, and lactose, NF.

What are the possible side effects of cabergoline (Dostinex)?

Get emergency medical help if you have any of these signs of an allergic reaction: hives; difficulty breathing; swelling of your face, lips, tongue, or throat.

Stop using cabergoline and call your doctor at once if you have any of these serious side effects:

  • cough or trouble breathing; or
  • feeling light-headed, fainting.

Less serious side effects may include:

  • nausea, vomiting, stomach pain, constipation;
  • headache;
  • dizziness, drowsiness, nervousness;
  • numbness or tingly feeling; or
  • hot...

Read All Potential Side Effects and See Pictures of Dostinex »

What are the precautions when taking cabergoline (Dostinex)?

Before taking cabergoline, tell your doctor or pharmacist if you are allergic to it; or to other ergot medications (such as ergotamine); or if you have any other allergies. This product may contain inactive ingredients, which can cause allergic reactions or other problems. Talk to your pharmacist for more details.

Before using this medication, tell your doctor or pharmacist your medical history, especially of: liver disease, high blood pressure (hypertension), heart valve disease, abnormal scarring/thickening of the lining in the lungs/heart/behind the abdomen (pulmonary/pericardial/retroperitoneal fibrosis).

This drug may make you dizzy. Do not drive, use machinery, or do any activity that requires alertness until you are sure you can perform such activities safely. Limit...

Read All Potential Precautions of Dostinex »

Last reviewed on RxList: 7/28/2011
This monograph has been modified to include the generic and brand name in many instances.

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Dostinex - User Reviews

Dostinex User Reviews

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Report Problems to the Food and Drug Administration

 

You are encouraged to report negative side effects of prescription drugs to the FDA. Visit the FDA MedWatch website or call 1-800-FDA-1088.


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