FOR TOPICAL DERMATOLOGIC USE ONLY.
Not for Ophthalmic, Oral or Intravaginal Use.
Dovonex® (calcipotriene) Cream, 0.005% contains calcipotriene monohydrate, a synthetic vitamin D3 derivative, for topical dermatological use.
Chemically, calcipotriene monohydrate is (5Z,7E,22E,24S)-24-cyclopropyl-9,10-secochola-5,7,10(19), 22-tetraene-1a,3b,24-triol monohydrate, with the empirical formula C27H40O3†H2O, a molecular weight of 430.6, and the following structural formula:
Calcipotriene monohydrate is a white or off-white crystalline substance. Dovonex Cream (calcipotriene cream) contains calcipotriene monohydrate equivalent to 50 µg/g anhydrous calcipotriene in a cream base of cetearyl alcohol, ceteth-20, diazolidinyl urea, dichlorobenzyl alcohol, dibasic sodium phosphate, edetate disodium, glycerin, mineral oil, petrolatum, and water.
What are the possible side effects of calcipotriene topical (Dovonex)?
Serious side effects are very rare. Stop using calcipotriene topical and seek emergency medical attention if you experience an allergic reaction (shortness of breath; closing of your throat; swelling of your lips, face, or tongue; or hives).
You may experience some irritation of the skin, such as burning, itching, redness, swelling, dryness, or peeling while you are using calcipotriene topical. These side effects sometimes lessen with continued treatment. Notify your doctor if you experience these side effects.
If you notice a change in your skin color, contact your...
What are the precautions when taking calcipotriene cream (Dovonex Cream)?
Before using this medication, tell your doctor or pharmacist if you are allergic to it; or if you have any other allergies. This product may contain inactive ingredients, which can cause allergic reactions or other problems. Talk to your pharmacist for more details.
This medication should not be used if you have certain medical conditions. Before using this medicine, consult your doctor or pharmacist if you have: high calcium/vitamin D levels (hypercalcemia/hypervitaminosis D).
Before using this medication, tell your doctor or pharmacist your medical history.
This medication may make you more sensitive to the sun. Avoid prolonged sun exposure, tanning booths, and sunlamps. Use a sunscreen and wear protective clothing when outdoors. Your doctor may direct you to...
Last reviewed on RxList: 9/23/2005
This monograph has been modified to include the generic and brand name in many instances.
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