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Doxil

"The U.S. Food and Drug Administration today approved the first generic version of the cancer drug Doxil (doxorubicin hydrochloride liposome injection).

Doxorubicin hydrochloride liposome injection is currently on the FDA’s drug sh"...

Doxil

OVERDOSE

Acute overdosage with doxorubicin HCl causes increases in mucositis, leucopenia, and thrombocytopenia.

Treatment of acute overdosage consists of treatment of the severely myelosuppressed patient with hospitalization, antibiotics, platelet and granulocyte transfusions, and symptomatic treatment of mucositis.

CONTRAINDICATIONS

DOXIL (doxorubicin HCl liposome injection) is contraindicated in patients who have a history of hypersensitivity reactions to a conventional formulation of doxorubicin HCl or the components of DOXIL [see WARNINGS and PRECAUTIONS].

DOXIL (doxorubicin hcl liposome injection) is contraindicated in nursing mothers [see Use in Specific Populations].

Last reviewed on RxList: 7/8/2008
This monograph has been modified to include the generic and brand name in many instances.

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