Drug interactions with abiraterone oral and mexiletine oral

abiraterone oral brand names and other generic formulations include:

Zytiga Oral

All generic drug interactions for abiraterone oral (lists will include brand and generic names):

mexiletine oral brand names and other generic formulations include:

Mexitil Oral

All generic drug interactions for mexiletine oral (lists will include brand and generic names):
Significant - Monitor CloselySignificant interaction possible (monitoring by your doctor required)

abiraterone oral and mexiletine oral

abiraterone oral increases levels of mexiletine oral by altering drug metabolism. Avoid taking abiraterone in this combination (with substrates of CYP2D6). If alternatives cannot be used, caution should be taken and consider a dose reduction of the CYP2D6 substrate.

Patient Drug Interactions Source: RxList
© 2014 RxList, Inc.
Significant - Monitor CloselySignificant interaction possible, monitor closely.

abiraterone oral and mexiletine oral

abiraterone oral increases levels of mexiletine oral by affecting hepatic enzyme CYP2D6 metabolism. Avoid coadministration of abiraterone with substrates of CYP2D6. If alternative therapy cannot be used, exercise caution and consider a dose reduction of the CYP2D6 substrate.

Clinical Drug Interactions Source: Medscape from WebMD
© 1994-2014 WebMD, LLC.
Significant - Monitor CloselySignificant interaction possible (monitoring by your doctor required)

mexiletine oral and abiraterone oral

mexiletine oral increases levels of abiraterone oral by altering drug metabolism. Avoid taking abiraterone in this combination (with substrates of CYP2D6). If alternatives cannot be used, caution should be taken and consider a dose reduction of the CYP2D6 substrate.

Patient Drug Interactions Source: RxList
© 2014 RxList, Inc.
Significant - Monitor CloselySignificant interaction possible, monitor closely.

mexiletine oral and abiraterone oral

mexiletine oral increases levels of abiraterone oral by affecting hepatic enzyme CYP2D6 metabolism. Avoid coadministration of abiraterone with substrates of CYP2D6. If alternative therapy cannot be used, exercise caution and consider a dose reduction of the CYP2D6 substrate.

Clinical Drug Interactions Source: Medscape from WebMD
© 1994-2014 WebMD, LLC.

Check for more interactions with the Drug Interaction Checker

Drug Interaction Categories

Contraindicated

Never use this combination of drugs because of high risk for dangerous interaction

Serious

Potential for serious interaction; regular monitoring by your doctor required or alternate medication may be needed

Significant

Potential for significant interaction (monitoring by your doctor is likely required)

Minor

Interaction is unlikely, minor, or nonsignificant

Disclaimer: The information contained herein should NOT be used as a substitute for the advice of an appropriately qualified and licensed physician or other health care provider. The information provided here is for informational purposes only. This tool may not cover all possible drug interactions. Please check with a physician if you have health questions or concerns. Although we attempt to provide accurate and up-to-date information, no guarantee is made to that effect.

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