Drug interactions with amlodipine-valsartan oral and simvastatin oral

amlodipine-valsartan oral brand names and other generic formulations include:

Exforge Oral

All generic drug interactions for amlodipine-valsartan oral (lists will include brand and generic names):

simvastatin oral brand names and other generic formulations include:

Zocor Oral

All generic drug interactions for simvastatin oral (lists will include brand and generic names):
Serious - Use AlternativePotential for serious interaction; regular monitoring by your doctor required or alternate medication may be needed

amlodipine-valsartan oral and simvastatin oral

amlodipine-valsartan oral increases levels of simvastatin oral by Other mechanism. Benefits of taking these drugs together should be carefully weighed against the potential risks of combination. Potential for increased risk of muscle damage/breakdown (myopathy/rhabdomyolysis). Limit simvastatin dose to no more than 20 mg/day when taken

Patient Drug Interactions Source: RxList
© 2014 RxList, Inc.
Serious - Use AlternativePossible serious or life-threatening interaction. Monitor closely. Use alternatives if available.

amlodipine-valsartan oral and simvastatin oral

amlodipine-valsartan oral increases levels of simvastatin oral by Other (see comment). Benefits of combination therapy should be carefully weighed against the potential risks of combination. Potential for increased risk of myopathy/rhabdomyolysis. Limit simvastatin dose to no more than 20 mg/day when used concurrently.

Clinical Drug Interactions Source: Medscape from WebMD
© 1994-2014 WebMD, LLC.
Serious - Use AlternativePotential for interaction

simvastatin oral and amlodipine-valsartan oral

simvastatin oral will increase the level or effect of amlodipine-valsartan oral by Other mechanism. Increased levels or effect of valsartan.

Patient Drug Interactions Source: RxList
© 2014 RxList, Inc.
Serious - Use AlternativePotential for interaction, monitor.

simvastatin oral and amlodipine-valsartan oral

simvastatin oral will increase the level or effect of amlodipine-valsartan oral by Other (see comment). The results from an in vitro study with human liver tissue indicate that valsartan is a substrate of the hepatic uptake transporter OATP1B1; coadministration with OATP1B1 inhibitors may increase valsartan systemic exposure

Clinical Drug Interactions Source: Medscape from WebMD
© 1994-2014 WebMD, LLC.

Check for more interactions with the Drug Interaction Checker

Drug Interaction Categories

Contraindicated

Never use this combination of drugs because of high risk for dangerous interaction

Serious

Potential for serious interaction; regular monitoring by your doctor required or alternate medication may be needed

Significant

Potential for significant interaction (monitoring by your doctor is likely required)

Minor

Interaction is unlikely, minor, or nonsignificant

Disclaimer: The information contained herein should NOT be used as a substitute for the advice of an appropriately qualified and licensed physician or other health care provider. The information provided here is for informational purposes only. This tool may not cover all possible drug interactions. Please check with a physician if you have health questions or concerns. Although we attempt to provide accurate and up-to-date information, no guarantee is made to that effect.

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