Drug interactions with boceprevir oral and sirolimus oral

boceprevir oral brand names and other generic formulations include:

Victrelis Oral

All generic drug interactions for boceprevir oral (lists will include brand and generic names):

sirolimus oral brand names and other generic formulations include:

Rapamune Oral

All generic drug interactions for sirolimus oral (lists will include brand and generic names):
Significant - Monitor CloselySignificant interaction possible (monitoring by your doctor required)

boceprevir oral and sirolimus oral

boceprevir oral increases levels of sirolimus oral by altering drug metabolism. May significantly increase blood levels of sirolimus. Close monitoring of sirolimus blood levels is required.

Patient Drug Interactions Source: RxList
© 2014 RxList, Inc.
Significant - Monitor CloselySignificant interaction possible, monitor closely.

boceprevir oral and sirolimus oral

boceprevir oral increases levels of sirolimus oral by affecting hepatic/intestinal enzyme CYP3A4 metabolism. Plasma concentrations of sirolimus are expected to be increased significantly during coadministration with boceprevir. Close monitoring of immunosuppressant blood levels is recommended.

Clinical Drug Interactions Source: Medscape from WebMD
© 1994-2014 WebMD, LLC.
Significant - Monitor CloselySignificant interaction possible (monitoring by your doctor required)

sirolimus oral and boceprevir oral

sirolimus oral increases levels of boceprevir oral by altering drug metabolism. May significantly increase blood levels of sirolimus. Close monitoring of sirolimus blood levels is required.

Patient Drug Interactions Source: RxList
© 2014 RxList, Inc.
Significant - Monitor CloselySignificant interaction possible, monitor closely.

sirolimus oral and boceprevir oral

sirolimus oral increases levels of boceprevir oral by affecting hepatic/intestinal enzyme CYP3A4 metabolism. Plasma concentrations of sirolimus are expected to be increased significantly during coadministration with boceprevir. Close monitoring of immunosuppressant blood levels is recommended.

Clinical Drug Interactions Source: Medscape from WebMD
© 1994-2014 WebMD, LLC.

Check for more interactions with the Drug Interaction Checker

Drug Interaction Categories

Contraindicated

Never use this combination of drugs because of high risk for dangerous interaction

Serious

Potential for serious interaction; regular monitoring by your doctor required or alternate medication may be needed

Significant

Potential for significant interaction (monitoring by your doctor is likely required)

Minor

Interaction is unlikely, minor, or nonsignificant

Disclaimer: The information contained herein should NOT be used as a substitute for the advice of an appropriately qualified and licensed physician or other health care provider. The information provided here is for informational purposes only. This tool may not cover all possible drug interactions. Please check with a physician if you have health questions or concerns. Although we attempt to provide accurate and up-to-date information, no guarantee is made to that effect.

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