Drug interactions with carvedilol phosphate oral and topotecan oral

carvedilol phosphate oral brand names and other generic formulations include:

Coreg CR Oral

All generic drug interactions for carvedilol phosphate oral (lists will include brand and generic names):

topotecan oral brand names and other generic formulations include:

Hycamtin Oral

All generic drug interactions for topotecan oral (lists will include brand and generic names):
Serious - Use AlternativePotential for serious interaction; regular monitoring by your doctor required

carvedilol phosphate oral and topotecan oral

carvedilol phosphate oral will increase the level or effect of topotecan oral by affects how the drug is eliminated from the body (via what is known as the P-glycoprotein [MDR1] transporter). Product labeling for oral topotecan recommends avoiding this drug combination. The interaction with intravenous topotecan may be less severe but still likely of clinical significance.

Patient Drug Interactions Source: RxList
© 2014 RxList, Inc.
Serious - Use AlternativeHigh likelihood serious or life-threatening interaction. Contraindicated unless benefits outweigh risks and no alternatives available.

carvedilol phosphate oral and topotecan oral

carvedilol phosphate oral will increase the level or effect of topotecan oral by P-glycoprotein (MDR1) efflux transporter. Product labeling for oral topotecan recommends avoiding use of p-glycoprotein inhibitors with oral topotecan. The interaction with intravenous topotecan may be less severe but still likely of clinical significance.

Clinical Drug Interactions Source: Medscape from WebMD
© 1994-2014 WebMD, LLC.
Serious - Use AlternativePotential for serious interaction; regular monitoring by your doctor required

topotecan oral and carvedilol phosphate oral

topotecan oral will increase the level or effect of carvedilol phosphate oral by affects how the drug is eliminated from the body (via what is known as the P-glycoprotein [MDR1] transporter). Product labeling for oral topotecan recommends avoiding this drug combination. The interaction with intravenous topotecan may be less severe but still likely of clinical significance.

Patient Drug Interactions Source: RxList
© 2014 RxList, Inc.
Serious - Use AlternativeHigh likelihood serious or life-threatening interaction. Contraindicated unless benefits outweigh risks and no alternatives available.

topotecan oral and carvedilol phosphate oral

topotecan oral will increase the level or effect of carvedilol phosphate oral by P-glycoprotein (MDR1) efflux transporter. Product labeling for oral topotecan recommends avoiding use of p-glycoprotein inhibitors with oral topotecan. The interaction with intravenous topotecan may be less severe but still likely of clinical significance.

Clinical Drug Interactions Source: Medscape from WebMD
© 1994-2014 WebMD, LLC.

Check for more interactions with the Drug Interaction Checker

Drug Interaction Categories

Contraindicated

Never use this combination of drugs because of high risk for dangerous interaction

Serious

Potential for serious interaction; regular monitoring by your doctor required or alternate medication may be needed

Significant

Potential for significant interaction (monitoring by your doctor is likely required)

Minor

Interaction is unlikely, minor, or nonsignificant

Disclaimer: The information contained herein should NOT be used as a substitute for the advice of an appropriately qualified and licensed physician or other health care provider. The information provided here is for informational purposes only. This tool may not cover all possible drug interactions. Please check with a physician if you have health questions or concerns. Although we attempt to provide accurate and up-to-date information, no guarantee is made to that effect.

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