Drug interactions with crizotinib oral and quinidine gluconate oral

crizotinib oral brand names and other generic formulations include:

Xalkori Oral

All generic drug interactions for crizotinib oral (lists will include brand and generic names):

quinidine gluconate oral brand names and other generic formulations include:

Quinadure Oral, Quinagen Duratab Oral, Quinaglute Dura-Tabs Oral, Quinalan Oral, Quinatime Oral, Quin-G Oral, Quing-G Oral, Quinitime Oral

All generic drug interactions for quinidine gluconate oral (lists will include brand and generic names):
Serious - Use AlternativePotential for serious interaction; regular monitoring by your doctor required or alternate medication may be needed

crizotinib oral and quinidine gluconate oral

crizotinib oral increases levels of quinidine gluconate oral by altering drug metabolism. Taking these drugs together should be avoided; ECG monitoring recommended.

Patient Drug Interactions Source: RxList
© 2014 RxList, Inc.
Serious - Use AlternativePossible serious or life-threatening interaction. Monitor closely. Use alternatives if available.

crizotinib oral and quinidine gluconate oral

crizotinib oral increases levels of quinidine gluconate oral by affecting hepatic/intestinal enzyme CYP3A4 metabolism. Coadministration of crizotinib with CYP3A substrates with narrow therapeutic indices should be avoided. ECG monitoring is recommended, along with drugs that may prolong the QT interval.

Clinical Drug Interactions Source: Medscape from WebMD
© 1994-2014 WebMD, LLC.
Serious - Use AlternativePotential for serious interaction; regular monitoring by your doctor required or alternate medication may be needed

quinidine gluconate oral and crizotinib oral

quinidine gluconate oral increases levels of crizotinib oral by altering drug metabolism. Taking these drugs together should be avoided; ECG monitoring recommended.

Patient Drug Interactions Source: RxList
© 2014 RxList, Inc.
Serious - Use AlternativePossible serious or life-threatening interaction. Monitor closely. Use alternatives if available.

quinidine gluconate oral and crizotinib oral

quinidine gluconate oral increases levels of crizotinib oral by affecting hepatic/intestinal enzyme CYP3A4 metabolism. Coadministration of crizotinib with CYP3A substrates with narrow therapeutic indices should be avoided. ECG monitoring is recommended, along with drugs that may prolong the QT interval.

Clinical Drug Interactions Source: Medscape from WebMD
© 1994-2014 WebMD, LLC.

Check for more interactions with the Drug Interaction Checker

Drug Interaction Categories

Contraindicated

Never use this combination of drugs because of high risk for dangerous interaction

Serious

Potential for serious interaction; regular monitoring by your doctor required or alternate medication may be needed

Significant

Potential for significant interaction (monitoring by your doctor is likely required)

Minor

Interaction is unlikely, minor, or nonsignificant

Disclaimer: The information contained herein should NOT be used as a substitute for the advice of an appropriately qualified and licensed physician or other health care provider. The information provided here is for informational purposes only. This tool may not cover all possible drug interactions. Please check with a physician if you have health questions or concerns. Although we attempt to provide accurate and up-to-date information, no guarantee is made to that effect.

Women's Health

Find out what women really need.


NIH talks about Ebola on WebMD