Drug interactions with crizotinib oral and saquinavir mesylate oral

crizotinib oral brand names and other generic formulations include:

Xalkori Oral

All generic drug interactions for crizotinib oral (lists will include brand and generic names):

saquinavir mesylate oral brand names and other generic formulations include:

Invirase Oral

All generic drug interactions for saquinavir mesylate oral (lists will include brand and generic names):
Significant - Monitor CloselySignificant interaction possible (monitoring by your doctor required)

crizotinib oral and saquinavir mesylate oral

crizotinib oral increases levels of saquinavir mesylate oral by altering drug metabolism. Avoid taking these medications together.

Patient Drug Interactions Source: RxList
© 2014 RxList, Inc.
Significant - Monitor CloselySignificant interaction possible, monitor closely.

crizotinib oral and saquinavir mesylate oral

crizotinib oral increases levels of saquinavir mesylate oral by affecting hepatic/intestinal enzyme CYP3A4 metabolism. Concomitant use of strong CYP3A inhibitors should be avoided. ECG monitoring is recommended, along with drugs that may prolong the QT interval.

Clinical Drug Interactions Source: Medscape from WebMD
© 1994-2014 WebMD, LLC.
Significant - Monitor CloselySignificant interaction possible (monitoring by your doctor required)

saquinavir mesylate oral and crizotinib oral

saquinavir mesylate oral increases levels of crizotinib oral by altering drug metabolism. Avoid taking these medications together.

Patient Drug Interactions Source: RxList
© 2014 RxList, Inc.
Significant - Monitor CloselySignificant interaction possible, monitor closely.

saquinavir mesylate oral and crizotinib oral

saquinavir mesylate oral increases levels of crizotinib oral by affecting hepatic/intestinal enzyme CYP3A4 metabolism. Concomitant use of strong CYP3A inhibitors should be avoided. ECG monitoring is recommended, along with drugs that may prolong the QT interval.

Clinical Drug Interactions Source: Medscape from WebMD
© 1994-2014 WebMD, LLC.

Check for more interactions with the Drug Interaction Checker

Drug Interaction Categories

Contraindicated

Never use this combination of drugs because of high risk for dangerous interaction

Serious

Potential for serious interaction; regular monitoring by your doctor required or alternate medication may be needed

Significant

Potential for significant interaction (monitoring by your doctor is likely required)

Minor

Interaction is unlikely, minor, or nonsignificant

Disclaimer: The information contained herein should NOT be used as a substitute for the advice of an appropriately qualified and licensed physician or other health care provider. The information provided here is for informational purposes only. This tool may not cover all possible drug interactions. Please check with a physician if you have health questions or concerns. Although we attempt to provide accurate and up-to-date information, no guarantee is made to that effect.

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