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Drug interactions with isoniazid-rifamp-pyrazinamide oral and niacin-lovastatin oral

isoniazid-rifamp-pyrazinamide oral brand names and other generic formulations include:

Rifater Oral

All generic drug interactions for isoniazid-rifamp-pyrazinamide oral (lists will include brand and generic names):

niacin-lovastatin oral brand names and other generic formulations include:

Advicor Oral

All generic drug interactions for niacin-lovastatin oral (lists will include brand and generic names):
ContraindicatedNever use this combination of drugs because of high risk for dangerous interaction

isoniazid-rifamp-pyrazinamide oral and niacin-lovastatin oral

isoniazid-rifamp-pyrazinamide oral will increase the level or effect of niacin-lovastatin oral by altering drug metabolism. The effectiveness of the statin will increase; Increasing the risk of muscle breakdown.

Patient Drug Interactions Source: RxList
© 2014 RxList, Inc.
ContraindicatedNever use combination.

isoniazid-rifamp-pyrazinamide oral and niacin-lovastatin oral

isoniazid-rifamp-pyrazinamide oral will increase the level or effect of niacin-lovastatin oral by affecting hepatic/intestinal enzyme CYP3A4 metabolism. Strong CYP3A4 inhibitors increase systemic statin exposure and risk of myopathy, including rhabdomyolysis

Clinical Drug Interactions Source: Medscape from WebMD
© 1994-2014 WebMD, LLC.

Check for more interactions with the Drug Interaction Checker

Drug Interaction Categories

Contraindicated

Never use this combination of drugs because of high risk for dangerous interaction

Serious

Potential for serious interaction; regular monitoring by your doctor required or alternate medication may be needed

Significant

Potential for significant interaction (monitoring by your doctor is likely required)

Minor

Interaction is unlikely, minor, or nonsignificant

Disclaimer: The information contained herein should NOT be used as a substitute for the advice of an appropriately qualified and licensed physician or other health care provider. The information provided here is for informational purposes only. This tool may not cover all possible drug interactions. Please check with a physician if you have health questions or concerns. Although we attempt to provide accurate and up-to-date information, no guarantee is made to that effect.

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