Drug interactions with isotretinoin oral and methotrexate sodium oral

isotretinoin oral brand names and other generic formulations include:

Absorica Oral, Accutane Oral, Amnesteem Oral, Claravis Oral, Myorisan Oral, Sotret Oral, Zenatane Oral

All generic drug interactions for isotretinoin oral (lists will include brand and generic names):

methotrexate sodium oral brand names and other generic formulations include:

Methotrexate (Anti-Rheumatic) Oral, Rheumatrex Oral, Trexall Oral

All generic drug interactions for methotrexate sodium oral (lists will include brand and generic names):
Significant - Monitor CloselySignificant interaction possible (monitoring by your doctor required)

isotretinoin oral and methotrexate sodium oral

isotretinoin oral , methotrexate sodium oral . Either increases toxicity of the other by added drug effects. There is an increased risk of liver related side effects of methotrexate; patients should be monitored closely during methotrexate therapy.

Patient Drug Interactions Source: RxList
© 2014 RxList, Inc.
Significant - Monitor CloselySignificant interaction possible, monitor closely.

isotretinoin oral and methotrexate sodium oral

isotretinoin oral , methotrexate sodium oral . Either increases toxicity of the other by pharmacodynamic synergism. Patients receiving other agents that may cause hepatotoxicity, including systemic retinoids, could be at increased risk of liver-related side effects of methotrexate and such patients should be monitored closely during methotrexate therapy.

Clinical Drug Interactions Source: Medscape from WebMD
© 1994-2014 WebMD, LLC.
Significant - Monitor CloselySignificant interaction possible (monitoring by your doctor required)

methotrexate sodium oral and isotretinoin oral

methotrexate sodium oral , isotretinoin oral . Either increases toxicity of the other by added drug effects. There is an increased risk of liver related side effects of methotrexate; patients should be monitored closely during methotrexate therapy.

Patient Drug Interactions Source: RxList
© 2014 RxList, Inc.
Significant - Monitor CloselySignificant interaction possible, monitor closely.

methotrexate sodium oral and isotretinoin oral

methotrexate sodium oral , isotretinoin oral . Either increases toxicity of the other by pharmacodynamic synergism. Patients receiving other agents that may cause hepatotoxicity, including systemic retinoids, could be at increased risk of liver-related side effects of methotrexate and such patients should be monitored closely during methotrexate therapy.

Clinical Drug Interactions Source: Medscape from WebMD
© 1994-2014 WebMD, LLC.

Check for more interactions with the Drug Interaction Checker

Drug Interaction Categories

Contraindicated

Never use this combination of drugs because of high risk for dangerous interaction

Serious

Potential for serious interaction; regular monitoring by your doctor required or alternate medication may be needed

Significant

Potential for significant interaction (monitoring by your doctor is likely required)

Minor

Interaction is unlikely, minor, or nonsignificant

Disclaimer: The information contained herein should NOT be used as a substitute for the advice of an appropriately qualified and licensed physician or other health care provider. The information provided here is for informational purposes only. This tool may not cover all possible drug interactions. Please check with a physician if you have health questions or concerns. Although we attempt to provide accurate and up-to-date information, no guarantee is made to that effect.

Women's Health

Find out what women really need.


NIH talks about Ebola on WebMD