Drug interactions with ivacaftor oral and norfloxacin oral

ivacaftor oral brand names and other generic formulations include:

Kalydeco Oral

All generic drug interactions for ivacaftor oral (lists will include brand and generic names):

norfloxacin oral brand names and other generic formulations include:

Noroxin Oral

All generic drug interactions for norfloxacin oral (lists will include brand and generic names):
Significant - Monitor CloselySignificant interaction possible (monitoring by your doctor required)

ivacaftor oral and norfloxacin oral

ivacaftor oral increases levels of norfloxacin oral by altering drug metabolism. May increase drug blood levels.

Patient Drug Interactions Source: RxList
© 2014 RxList, Inc.
Significant - Monitor CloselySignificant interaction possible, monitor closely.

ivacaftor oral and norfloxacin oral

ivacaftor oral increases levels of norfloxacin oral by affecting hepatic/intestinal enzyme CYP3A4 metabolism. Reduce ivacaftor dose to 150 mg once daily when coadministered with moderate CYP3A4 inhibitors

Clinical Drug Interactions Source: Medscape from WebMD
© 1994-2014 WebMD, LLC.
Significant - Monitor CloselySignificant interaction possible (monitoring by your doctor required)

norfloxacin oral and ivacaftor oral

norfloxacin oral increases levels of ivacaftor oral by altering drug metabolism. May increase drug blood levels.

Patient Drug Interactions Source: RxList
© 2014 RxList, Inc.
Significant - Monitor CloselySignificant interaction possible, monitor closely.

norfloxacin oral and ivacaftor oral

norfloxacin oral increases levels of ivacaftor oral by affecting hepatic/intestinal enzyme CYP3A4 metabolism. Reduce ivacaftor dose to 150 mg once daily when coadministered with moderate CYP3A4 inhibitors

Clinical Drug Interactions Source: Medscape from WebMD
© 1994-2014 WebMD, LLC.

Check for more interactions with the Drug Interaction Checker

Drug Interaction Categories

Contraindicated

Never use this combination of drugs because of high risk for dangerous interaction

Serious

Potential for serious interaction; regular monitoring by your doctor required or alternate medication may be needed

Significant

Potential for significant interaction (monitoring by your doctor is likely required)

Minor

Interaction is unlikely, minor, or nonsignificant

Disclaimer: The information contained herein should NOT be used as a substitute for the advice of an appropriately qualified and licensed physician or other health care provider. The information provided here is for informational purposes only. This tool may not cover all possible drug interactions. Please check with a physician if you have health questions or concerns. Although we attempt to provide accurate and up-to-date information, no guarantee is made to that effect.

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