Drug interactions with ivacaftor oral and norgestimate-ethinyl estradiol oral

ivacaftor oral brand names and other generic formulations include:

Kalydeco Oral

All generic drug interactions for ivacaftor oral (lists will include brand and generic names):

norgestimate-ethinyl estradiol oral brand names and other generic formulations include:

Estarylla Oral, Mono-Linyah Oral, Mononessa (28) Oral, Ortho Tri-Cyclen (21) Oral, Ortho Tri-Cyclen (28) Oral, Ortho Tri-Cyclen Lo (28) Oral, Ortho-Cyclen (21) Oral, Ortho-Cyclen (28) Oral, Previfem Oral, Sprintec (28) Oral, Tri-Estarylla Oral, Tri-Linyah Oral, Tri-Lo-Sprintec Oral, TriNessa (28) Oral, Tri-Previfem (28) Oral, Tri-Sprintec (28) Oral

All generic drug interactions for norgestimate-ethinyl estradiol oral (lists will include brand and generic names):
Serious - Use AlternativePotential for serious interaction; regular monitoring by your doctor required or alternate medication may be needed

ivacaftor oral and norgestimate-ethinyl estradiol oral

ivacaftor oral , norgestimate-ethinyl estradiol oral . Either increases levels of the other by altering drug metabolism. Blood levels of erythromycin may increase.

Patient Drug Interactions Source: RxList
© 2014 RxList, Inc.
Serious - Use AlternativePossible serious or life-threatening interaction. Monitor closely. Use alternatives if available.

ivacaftor oral and norgestimate-ethinyl estradiol oral

ivacaftor oral , norgestimate-ethinyl estradiol oral . Either increases levels of the other by affecting hepatic/intestinal enzyme CYP3A4 metabolism. Ivacaftor and its M1 metabolite has the potential to inhibit CYP3A4, may significantly increase systemic exposure to CYP3A4 substrates

Clinical Drug Interactions Source: Medscape from WebMD
© 1994-2014 WebMD, LLC.
Serious - Use AlternativePotential for serious interaction; regular monitoring by your doctor required or alternate medication may be needed

norgestimate-ethinyl estradiol oral and ivacaftor oral

norgestimate-ethinyl estradiol oral , ivacaftor oral . Either increases levels of the other by altering drug metabolism. Blood levels of erythromycin may increase.

Patient Drug Interactions Source: RxList
© 2014 RxList, Inc.
Serious - Use AlternativePossible serious or life-threatening interaction. Monitor closely. Use alternatives if available.

norgestimate-ethinyl estradiol oral and ivacaftor oral

norgestimate-ethinyl estradiol oral , ivacaftor oral . Either increases levels of the other by affecting hepatic/intestinal enzyme CYP3A4 metabolism. Ivacaftor and its M1 metabolite has the potential to inhibit CYP3A4, may significantly increase systemic exposure to CYP3A4 substrates

Clinical Drug Interactions Source: Medscape from WebMD
© 1994-2014 WebMD, LLC.

Check for more interactions with the Drug Interaction Checker

Drug Interaction Categories

Contraindicated

Never use this combination of drugs because of high risk for dangerous interaction

Serious

Potential for serious interaction; regular monitoring by your doctor required or alternate medication may be needed

Significant

Potential for significant interaction (monitoring by your doctor is likely required)

Minor

Interaction is unlikely, minor, or nonsignificant

Disclaimer: The information contained herein should NOT be used as a substitute for the advice of an appropriately qualified and licensed physician or other health care provider. The information provided here is for informational purposes only. This tool may not cover all possible drug interactions. Please check with a physician if you have health questions or concerns. Although we attempt to provide accurate and up-to-date information, no guarantee is made to that effect.

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