Drug interactions with ketoconazole oral and vismodegib oral

ketoconazole oral brand names and other generic formulations include:

Nizoral Oral

All generic drug interactions for ketoconazole oral (lists will include brand and generic names):

vismodegib oral brand names and other generic formulations include:

Erivedge Oral

All generic drug interactions for vismodegib oral (lists will include brand and generic names):
Significant - Monitor CloselyPotential for interaction

ketoconazole oral and vismodegib oral

ketoconazole oral will increase the level or effect of vismodegib oral by affects how the drug is eliminated from the body (via what is known as the P-glycoprotein [MDR1] transporter). Increased levels of vismodegib.

Patient Drug Interactions Source: RxList
© 2014 RxList, Inc.
Significant - Monitor CloselyPotential for interaction, monitor.

ketoconazole oral and vismodegib oral

ketoconazole oral will increase the level or effect of vismodegib oral by P-glycoprotein (MDR1) efflux transporter. Vismodegib is a substrate of efflux transporter P-glycoprotein (P-gp); coadministration with P-gp inhibitors increase vismodegib systemic exposure

Clinical Drug Interactions Source: Medscape from WebMD
© 1994-2014 WebMD, LLC.
Significant - Monitor CloselyPotential for interaction

vismodegib oral and ketoconazole oral

vismodegib oral will increase the level or effect of ketoconazole oral by affects how the drug is eliminated from the body (via what is known as the P-glycoprotein [MDR1] transporter). Increased levels of vismodegib.

Patient Drug Interactions Source: RxList
© 2014 RxList, Inc.
Significant - Monitor CloselyPotential for interaction, monitor.

vismodegib oral and ketoconazole oral

vismodegib oral will increase the level or effect of ketoconazole oral by P-glycoprotein (MDR1) efflux transporter. Vismodegib is a substrate of efflux transporter P-glycoprotein (P-gp); coadministration with P-gp inhibitors increase vismodegib systemic exposure

Clinical Drug Interactions Source: Medscape from WebMD
© 1994-2014 WebMD, LLC.

Check for more interactions with the Drug Interaction Checker

Drug Interaction Categories

Contraindicated

Never use this combination of drugs because of high risk for dangerous interaction

Serious

Potential for serious interaction; regular monitoring by your doctor required or alternate medication may be needed

Significant

Potential for significant interaction (monitoring by your doctor is likely required)

Minor

Interaction is unlikely, minor, or nonsignificant

Disclaimer: The information contained herein should NOT be used as a substitute for the advice of an appropriately qualified and licensed physician or other health care provider. The information provided here is for informational purposes only. This tool may not cover all possible drug interactions. Please check with a physician if you have health questions or concerns. Although we attempt to provide accurate and up-to-date information, no guarantee is made to that effect.

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