Drug interactions with lapatinib oral and tamoxifen oral

lapatinib oral brand names and other generic formulations include:

Tykerb Oral

All generic drug interactions for lapatinib oral (lists will include brand and generic names):

tamoxifen oral brand names and other generic formulations include:

Nolvadex Oral, Soltamox Oral

All generic drug interactions for tamoxifen oral (lists will include brand and generic names):
MinorInteraction is unlikely, minor, or nonsignificant

lapatinib oral and tamoxifen oral

lapatinib oral , tamoxifen oral altering drug metabolism. The effect of tamoxifen may be reduced.

Patient Drug Interactions Source: RxList
© 2014 RxList, Inc.
MinorMinor or non-significant interaction.

lapatinib oral and tamoxifen oral

lapatinib oral , tamoxifen oral affecting hepatic/intestinal enzyme CYP3A4 metabolism. CYP3A4 inhibition decreases metabolism of tamoxifen to N-desmethyl tamoxifen (active metabolite with similar biologic activity)

Clinical Drug Interactions Source: Medscape from WebMD
© 1994-2014 WebMD, LLC.
MinorInteraction is unlikely, minor, or nonsignificant

tamoxifen oral and lapatinib oral

tamoxifen oral , lapatinib oral altering drug metabolism. The effect of tamoxifen may be reduced.

Patient Drug Interactions Source: RxList
© 2014 RxList, Inc.
MinorMinor or non-significant interaction.

tamoxifen oral and lapatinib oral

tamoxifen oral , lapatinib oral affecting hepatic/intestinal enzyme CYP3A4 metabolism. CYP3A4 inhibition decreases metabolism of tamoxifen to N-desmethyl tamoxifen (active metabolite with similar biologic activity)

Clinical Drug Interactions Source: Medscape from WebMD
© 1994-2014 WebMD, LLC.

Check for more interactions with the Drug Interaction Checker

Drug Interaction Categories

Contraindicated

Never use this combination of drugs because of high risk for dangerous interaction

Serious

Potential for serious interaction; regular monitoring by your doctor required or alternate medication may be needed

Significant

Potential for significant interaction (monitoring by your doctor is likely required)

Minor

Interaction is unlikely, minor, or nonsignificant

Disclaimer: The information contained herein should NOT be used as a substitute for the advice of an appropriately qualified and licensed physician or other health care provider. The information provided here is for informational purposes only. This tool may not cover all possible drug interactions. Please check with a physician if you have health questions or concerns. Although we attempt to provide accurate and up-to-date information, no guarantee is made to that effect.

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