Drug interactions with niacin-simvastatin oral and trandolapril-verapamil oral

niacin-simvastatin oral brand names and other generic formulations include:

Simcor Oral

All generic drug interactions for niacin-simvastatin oral (lists will include brand and generic names):

trandolapril-verapamil oral brand names and other generic formulations include:

Tarka Oral

All generic drug interactions for trandolapril-verapamil oral (lists will include brand and generic names):
Serious - Use AlternativePotential for serious interaction; regular monitoring by your doctor required or alternate medication may be needed

niacin-simvastatin oral and trandolapril-verapamil oral

niacin-simvastatin oral will increase the level or effect of trandolapril-verapamil oral by altering drug metabolism. Do not exceed simvastatin 10 mg daily when taken together; Potential for increased risk of muscle damage (myopathy) including breakdown (rhabdomyolysis).

Patient Drug Interactions Source: RxList
© 2014 RxList, Inc.
Serious - Use AlternativePossible serious or life-threatening interaction. Monitor closely. Use alternatives if available.

niacin-simvastatin oral and trandolapril-verapamil oral

niacin-simvastatin oral will increase the level or effect of trandolapril-verapamil oral by affecting hepatic/intestinal enzyme CYP3A4 metabolism. Do not exceed simvastatin 10 mg daily when given concurrently. Potential for increased risk of myopathy/rhabdomyolysis.

Clinical Drug Interactions Source: Medscape from WebMD
© 1994-2014 WebMD, LLC.
Serious - Use AlternativePotential for serious interaction; regular monitoring by your doctor required or alternate medication may be needed

trandolapril-verapamil oral and niacin-simvastatin oral

trandolapril-verapamil oral will increase the level or effect of niacin-simvastatin oral by altering drug metabolism. Do not exceed simvastatin 10 mg daily when taken together; Potential for increased risk of muscle damage (myopathy) including breakdown (rhabdomyolysis).

Patient Drug Interactions Source: RxList
© 2014 RxList, Inc.
Serious - Use AlternativePossible serious or life-threatening interaction. Monitor closely. Use alternatives if available.

trandolapril-verapamil oral and niacin-simvastatin oral

trandolapril-verapamil oral will increase the level or effect of niacin-simvastatin oral by affecting hepatic/intestinal enzyme CYP3A4 metabolism. Do not exceed simvastatin 10 mg daily when given concurrently. Potential for increased risk of myopathy/rhabdomyolysis.

Clinical Drug Interactions Source: Medscape from WebMD
© 1994-2014 WebMD, LLC.

Check for more interactions with the Drug Interaction Checker

Drug Interaction Categories

Contraindicated

Never use this combination of drugs because of high risk for dangerous interaction

Serious

Potential for serious interaction; regular monitoring by your doctor required or alternate medication may be needed

Significant

Potential for significant interaction (monitoring by your doctor is likely required)

Minor

Interaction is unlikely, minor, or nonsignificant

Disclaimer: The information contained herein should NOT be used as a substitute for the advice of an appropriately qualified and licensed physician or other health care provider. The information provided here is for informational purposes only. This tool may not cover all possible drug interactions. Please check with a physician if you have health questions or concerns. Although we attempt to provide accurate and up-to-date information, no guarantee is made to that effect.

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