Drug interactions with nilotinib oral and ritonavir oral

nilotinib oral brand names and other generic formulations include:

Tasigna Oral

All generic drug interactions for nilotinib oral (lists will include brand and generic names):

ritonavir oral brand names and other generic formulations include:

Norvir Oral, Norvir Soft Gelatin Oral

All generic drug interactions for ritonavir oral (lists will include brand and generic names):
Significant - Monitor CloselySignificant interaction possible (monitoring by your doctor required)

nilotinib oral and ritonavir oral

nilotinib oral will increase the level or effect of ritonavir oral by altering drug metabolism.

Patient Drug Interactions Source: RxList
© 2014 RxList, Inc.
Significant - Monitor CloselySignificant interaction possible, monitor closely.

nilotinib oral and ritonavir oral

nilotinib oral will increase the level or effect of ritonavir oral by affecting hepatic/intestinal enzyme CYP3A4 metabolism.

Clinical Drug Interactions Source: Medscape from WebMD
© 1994-2014 WebMD, LLC.
Significant - Monitor CloselyPotential for serious interaction; regular monitoring by your doctor required or alternate medication may be needed

ritonavir oral and nilotinib oral

ritonavir oral will increase the level or effect of nilotinib oral by altering drug metabolism. Blood levels and effect of nilotinib may increase and increase risk for toxicity including prolonged QT interval (abnormal heart beats).

Patient Drug Interactions Source: RxList
© 2014 RxList, Inc.
Significant - Monitor CloselyPossible serious or life-threatening interaction. Monitor closely. Use alternatives if available.

ritonavir oral and nilotinib oral

ritonavir oral will increase the level or effect of nilotinib oral by affecting hepatic/intestinal enzyme CYP3A4 metabolism. May require decreased nilotinib dose or adjustment of dosing interval. Both ritonavir and nilotinib are CYP3A4 inhibitor, however, ritonavir is a strong CYP3A4 inhibitor and more likely to increase nilotinib levels and increase risk for toxicity including

Clinical Drug Interactions Source: Medscape from WebMD
© 1994-2014 WebMD, LLC.

Check for more interactions with the Drug Interaction Checker

Drug Interaction Categories

Contraindicated

Never use this combination of drugs because of high risk for dangerous interaction

Serious

Potential for serious interaction; regular monitoring by your doctor required or alternate medication may be needed

Significant

Potential for significant interaction (monitoring by your doctor is likely required)

Minor

Interaction is unlikely, minor, or nonsignificant

Disclaimer: The information contained herein should NOT be used as a substitute for the advice of an appropriately qualified and licensed physician or other health care provider. The information provided here is for informational purposes only. This tool may not cover all possible drug interactions. Please check with a physician if you have health questions or concerns. Although we attempt to provide accurate and up-to-date information, no guarantee is made to that effect.

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