Drug interactions with phenytoin oral and vinblastine iv

phenytoin oral brand names and other generic formulations include:

Dilantin Infatabs Oral, Dilantin-125 Oral, Lorantoin Oral

All generic drug interactions for phenytoin oral (lists will include brand and generic names):

vinblastine iv brand names and other generic formulations include:

Velban IV, Velsar IV

All generic drug interactions for vinblastine iv (lists will include brand and generic names):
MinorInteraction is unlikely, minor, or nonsignificant

phenytoin oral and vinblastine iv

phenytoin oral will decrease the level or effect of vinblastine iv by altering drug metabolism.

Patient Drug Interactions Source: RxList
© 2014 RxList, Inc.
MinorMinor or non-significant interaction.

phenytoin oral and vinblastine iv

phenytoin oral will decrease the level or effect of vinblastine iv by affecting hepatic/intestinal enzyme CYP3A4 metabolism.

Clinical Drug Interactions Source: Medscape from WebMD
© 1994-2014 WebMD, LLC.
MinorSignificant interaction possible (monitoring by your doctor required)

vinblastine iv and phenytoin oral

vinblastine iv will decrease the level or effect of phenytoin oral by affects how the drug is eliminated from the body (via what is known as the P-glycoprotein [MDR1] transporter). Combination may reduce phenytoin levels and lead to seizure.

Patient Drug Interactions Source: RxList
© 2014 RxList, Inc.
MinorSignificant interaction possible, monitor closely.

vinblastine iv and phenytoin oral

vinblastine iv will decrease the level or effect of phenytoin oral by P-glycoprotein (MDR1) efflux transporter. Concurrent use of vinblastine and phenytoin may reduce phenytoin plasma levels and increase seizure activity.

Clinical Drug Interactions Source: Medscape from WebMD
© 1994-2014 WebMD, LLC.

Check for more interactions with the Drug Interaction Checker

Drug Interaction Categories

Contraindicated

Never use this combination of drugs because of high risk for dangerous interaction

Serious

Potential for serious interaction; regular monitoring by your doctor required or alternate medication may be needed

Significant

Potential for significant interaction (monitoring by your doctor is likely required)

Minor

Interaction is unlikely, minor, or nonsignificant

Disclaimer: The information contained herein should NOT be used as a substitute for the advice of an appropriately qualified and licensed physician or other health care provider. The information provided here is for informational purposes only. This tool may not cover all possible drug interactions. Please check with a physician if you have health questions or concerns. Although we attempt to provide accurate and up-to-date information, no guarantee is made to that effect.

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