Drug interactions with quinidine gluconate oral and topotecan iv

quinidine gluconate oral brand names and other generic formulations include:

Quinadure Oral, Quinagen Duratab Oral, Quinaglute Dura-Tabs Oral, Quinalan Oral, Quinatime Oral, Quin-G Oral, Quing-G Oral, Quinitime Oral

All generic drug interactions for quinidine gluconate oral (lists will include brand and generic names):

topotecan iv brand names and other generic formulations include:

Hycamtin IV

All generic drug interactions for topotecan iv (lists will include brand and generic names):
Serious - Use AlternativePotential for serious interaction; regular monitoring by your doctor required

quinidine gluconate oral and topotecan iv

quinidine gluconate oral will increase the level or effect of topotecan iv by affects how the drug is eliminated from the body (via what is known as the P-glycoprotein [MDR1] transporter). Product labeling for oral topotecan recommends avoiding this drug combination. The interaction with intravenous topotecan may be less severe but still likely of clinical significance.

Patient Drug Interactions Source: RxList
© 2014 RxList, Inc.
Serious - Use AlternativeHigh likelihood serious or life-threatening interaction. Contraindicated unless benefits outweigh risks and no alternatives available.

quinidine gluconate oral and topotecan iv

quinidine gluconate oral will increase the level or effect of topotecan iv by P-glycoprotein (MDR1) efflux transporter. Product labeling for oral topotecan recommends avoiding use of p-glycoprotein inhibitors with oral topotecan. The interaction with intravenous topotecan may be less severe but still likely of clinical significance.

Clinical Drug Interactions Source: Medscape from WebMD
© 1994-2014 WebMD, LLC.
Serious - Use AlternativePotential for serious interaction; regular monitoring by your doctor required

topotecan iv and quinidine gluconate oral

topotecan iv will increase the level or effect of quinidine gluconate oral by affects how the drug is eliminated from the body (via what is known as the P-glycoprotein [MDR1] transporter). Product labeling for oral topotecan recommends avoiding this drug combination. The interaction with intravenous topotecan may be less severe but still likely of clinical significance.

Patient Drug Interactions Source: RxList
© 2014 RxList, Inc.
Serious - Use AlternativeHigh likelihood serious or life-threatening interaction. Contraindicated unless benefits outweigh risks and no alternatives available.

topotecan iv and quinidine gluconate oral

topotecan iv will increase the level or effect of quinidine gluconate oral by P-glycoprotein (MDR1) efflux transporter. Product labeling for oral topotecan recommends avoiding use of p-glycoprotein inhibitors with oral topotecan. The interaction with intravenous topotecan may be less severe but still likely of clinical significance.

Clinical Drug Interactions Source: Medscape from WebMD
© 1994-2014 WebMD, LLC.

Check for more interactions with the Drug Interaction Checker

Drug Interaction Categories

Contraindicated

Never use this combination of drugs because of high risk for dangerous interaction

Serious

Potential for serious interaction; regular monitoring by your doctor required or alternate medication may be needed

Significant

Potential for significant interaction (monitoring by your doctor is likely required)

Minor

Interaction is unlikely, minor, or nonsignificant

Disclaimer: The information contained herein should NOT be used as a substitute for the advice of an appropriately qualified and licensed physician or other health care provider. The information provided here is for informational purposes only. This tool may not cover all possible drug interactions. Please check with a physician if you have health questions or concerns. Although we attempt to provide accurate and up-to-date information, no guarantee is made to that effect.

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