Drug interactions with rifabutin oral and saquinavir base oral

rifabutin oral brand names and other generic formulations include:

Mycobutin Oral

All generic drug interactions for rifabutin oral (lists will include brand and generic names):

saquinavir base oral brand names and other generic formulations include:

Fortovase Oral

All generic drug interactions for saquinavir base oral (lists will include brand and generic names):
Significant - Monitor CloselyPotential for interaction

rifabutin oral and saquinavir base oral

rifabutin oral decreases levels of saquinavir base oral by speeding up drug metabolism. If saquinavir is taken with ritonavir as boosted therapy, the interaction is not clinically significant.

Patient Drug Interactions Source: RxList
© 2014 RxList, Inc.
Significant - Monitor CloselyPotential for interaction, monitor.

rifabutin oral and saquinavir base oral

rifabutin oral decreases levels of saquinavir base oral by increasing metabolism. If saquinavir administered with ritonavir as boosted therapy, interaction not clinically significant.

Clinical Drug Interactions Source: Medscape from WebMD
© 1994-2014 WebMD, LLC.
Significant - Monitor CloselyPotential for serious interaction; regular monitoring by your doctor required or alternate medication may be needed

saquinavir base oral and rifabutin oral

saquinavir base oral will decrease the level or effect of rifabutin oral by altering drug metabolism. Caution; usage together may reduce rifbutin by 75%; check with the doctor before use.

Patient Drug Interactions Source: RxList
© 2014 RxList, Inc.
Significant - Monitor CloselyPossible serious or life-threatening interaction. Monitor closely. Use alternatives if available.

saquinavir base oral and rifabutin oral

saquinavir base oral will decrease the level or effect of rifabutin oral by affecting hepatic/intestinal enzyme CYP3A4 metabolism. Dosage reduction of rifabutin by at least 75% of the usual dose of 300 mg/day is recommended (ie, a maximum dose of 150 mg every other day or 3 times/week). Increased monitoring for adverse events is warranted in patients receiving the combination. Consid

Clinical Drug Interactions Source: Medscape from WebMD
© 1994-2014 WebMD, LLC.

Check for more interactions with the Drug Interaction Checker

Drug Interaction Categories

Contraindicated

Never use this combination of drugs because of high risk for dangerous interaction

Serious

Potential for serious interaction; regular monitoring by your doctor required or alternate medication may be needed

Significant

Potential for significant interaction (monitoring by your doctor is likely required)

Minor

Interaction is unlikely, minor, or nonsignificant

Disclaimer: The information contained herein should NOT be used as a substitute for the advice of an appropriately qualified and licensed physician or other health care provider. The information provided here is for informational purposes only. This tool may not cover all possible drug interactions. Please check with a physician if you have health questions or concerns. Although we attempt to provide accurate and up-to-date information, no guarantee is made to that effect.

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