Drug interactions with saquinavir mesylate oral and sitagliptin-simvastatin oral

saquinavir mesylate oral brand names and other generic formulations include:

Invirase Oral

All generic drug interactions for saquinavir mesylate oral (lists will include brand and generic names):

sitagliptin-simvastatin oral brand names and other generic formulations include:

Juvisync Oral

All generic drug interactions for sitagliptin-simvastatin oral (lists will include brand and generic names):
ContraindicatedNever use this combination of drugs because of high risk for dangerous interaction

saquinavir mesylate oral and sitagliptin-simvastatin oral

saquinavir mesylate oral increases levels of sitagliptin-simvastatin oral by altering drug metabolism. Do not use together; Increased risk for rhabdomyolysis (muscle breakdown) with drugs that increase simvastatin systemic exposure.

Patient Drug Interactions Source: RxList
© 2014 RxList, Inc.
ContraindicatedNever use combination.

saquinavir mesylate oral and sitagliptin-simvastatin oral

saquinavir mesylate oral increases levels of sitagliptin-simvastatin oral by affecting hepatic/intestinal enzyme CYP3A4 metabolism. Contraindicated. Increased risk for rhabdomyolysis with drugs that increase simvastatin systemic exposure

Clinical Drug Interactions Source: Medscape from WebMD
© 1994-2014 WebMD, LLC.
ContraindicatedNever use this combination of drugs because of high risk for dangerous interaction

sitagliptin-simvastatin oral and saquinavir mesylate oral

sitagliptin-simvastatin oral will increase the level or effect of saquinavir mesylate oral by affects how the drug is eliminated from the body (via what is known as the P-glycoprotein [MDR1] transporter).

Patient Drug Interactions Source: RxList
© 2014 RxList, Inc.
ContraindicatedNever use combination.

sitagliptin-simvastatin oral and saquinavir mesylate oral

sitagliptin-simvastatin oral will increase the level or effect of saquinavir mesylate oral by P-glycoprotein (MDR1) efflux transporter.

Clinical Drug Interactions Source: Medscape from WebMD
© 1994-2014 WebMD, LLC.

Check for more interactions with the Drug Interaction Checker

Drug Interaction Categories

Contraindicated

Never use this combination of drugs because of high risk for dangerous interaction

Serious

Potential for serious interaction; regular monitoring by your doctor required or alternate medication may be needed

Significant

Potential for significant interaction (monitoring by your doctor is likely required)

Minor

Interaction is unlikely, minor, or nonsignificant

Disclaimer: The information contained herein should NOT be used as a substitute for the advice of an appropriately qualified and licensed physician or other health care provider. The information provided here is for informational purposes only. This tool may not cover all possible drug interactions. Please check with a physician if you have health questions or concerns. Although we attempt to provide accurate and up-to-date information, no guarantee is made to that effect.

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