August 24, 2016

Medications known to have significant interactions with diphenhydramine-phenylephrine oral

Brand Names Include:

Ala-Hist LQ Oral, Aldex-CT Oral, Benadryl-D Allergy-Sinus Oral, Child Allergy & Sinus D Oral, Child Delsym Cough-Cold Night Oral, Child Delsym Nighttime C-C Oral, Child's Benadryl-D Allergy-Sin Oral, Childs Triacting Cold & Cough Oral, Complete Allergy & Sinus-D Oral, Delsym Night Time Cough & Cold Oral, DHM-PE Oral, Nighttime Cough-Cold Oral, Pediacare Allergy & Cold Oral, phenyleph/diphenhyd-phenyleph Oral, Sudafed PE Day & Night Oral, Triaminic Cold & Cough NT (PE) Oral, Wal-Dryl-D Allergy & Sinus Oral, Zoden PD Oral

All generic drug interactions for diphenhydramine-phenylephrine oral (lists will include brand and generic names):

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  • No matching drugs found

Check for more interactions with the Drug Interaction Checker

Drug Interaction Categories


Never use this combination of drugs because of high risk for dangerous interaction


Potential for serious interaction; regular monitoring by your doctor required or alternate medication may be needed


Potential for significant interaction (monitoring by your doctor is likely required)


Interaction is unlikely, minor, or nonsignificant

Disclaimer: The information contained herein should NOT be used as a substitute for the advice of an appropriately qualified and licensed physician or other health care provider. The information provided here is for informational purposes only. This tool may not cover all possible drug interactions. Please check with a physician if you have health questions or concerns. Although we attempt to provide accurate and up-to-date information, no guarantee is made to that effect.

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