Medications known to have significant interactions with pseudoephedrine-guaifenesin oral

Brand Names Include:

Aber-Fed Oral, AbleTex PSE Oral, Aldex GS Oral, Altarussin PE Oral, ALTEX-PSE Oral, Ambi 40PSE-400GFN Oral, AMBI 45-800 Oral, AMBI 60-1000 Oral, AMBI 60-580 Oral, Ambi 60PSE-400GFN Oral, AMBI 80-700 Oral, AMBI 80-780 Oral, Ambifed Oral, Ambifed-G (IR) Oral, Ambifed-G Oral, Amitex PSE Oral, Anatuss LA Oral, Antitussive Pe Oral, Aquatab D Dose Pack Oral, Biotuss PE Oral, Boca-Tex PSE Oral, Brexin Ex Oral, Centex-PSE Oral, Ceritussin-Pe Oral, Chest And Nasal Congestion Oral, Chest Congestion Relief D Oral, Coldmist JR Oral, Coldmist LA Oral, Coldmist S Oral, Congess JR Oral, Congess SR Oral, Congestac Oral, Congest-Eze Oral, Conpec L.A. Oral, Cough Control PE Oral, Cough Formula PE Oral, Deco-D Oral, Decongest II Oral, Decongestant II Oral, Decongestant Pe Cough Formula Oral, Deconsal LA Oral, Defen-LA Oral, Degen II Oral, Demibid II Oral, Desal-II Oral, Despec SR Oral, Despec-Tab Oral, Dex-500 Oral, D-Feda II Oral, D-PSE/GG Oral, Drituss GP Oral, Duraphen Oral, Durasal II Oral, Duratuss AM-PM Oral, Dynex Oral, E-D Oral, Enomine PSE Oral, Entex PSE Oral, Entex T Oral, Eudal-SR Oral, ExeFen Oral, ExeFen-IR Oral, Expectorant PE Sugar-Free Oral, Expressin 400 Oral, Ex-Span Oral, Fenex-Pse Oral, G/P 1200/60 Oral, Geofed Oral, G-Fed Oral, G-Fed Ped Oral, GFN 1200-PSE 50 Oral, GFN 550-PSE 60 Oral, GFN 595-PSE 48 Tab Oral, GFN 795-PSE 85 Tab Oral, GFN 800-PSE 60 Oral, GFN/PSE Oral, Glyatuss Pe Oral, Glycofed Oral, G-P Oral, GP500 Oral, G-Phed Oral, G-Phed-PD Oral, Guaiatussin Pe Oral, Guaibid D Oral, Guaibid D Pediatric Oral, Guaifed-PSE Oral, Guaifen PSE Oral, Guaifenesin 600/PSE 120 Oral, Guaifenesin PSE SR Oral, Guaifenesin-P Oral, Guaifenesin-P-PD Oral, Guaifenesin-PSE Oral, Guaifenex GP Oral, Guaifenex PSE 120 Oral, Guaifenex PSE 60 Oral, Guaifenex PSE 80 Oral, Guaifenex PSE 85 Oral, Guaifenex-Rx Oral, GuaiMAX-D Oral, Guaimist S Oral, Guai-Sudo Oral, Guaitab Oral, Guaivent PD Oral, Guai-Vent/PSE Oral, Guiacough Pe Oral, Guiadrine GP Oral, Guiadrine II Oral, Guiadrine Oral, Guiadrine PSE 120 Oral, Guiadrine PSE Oral, Guiafed Oral, GUIAFEN-PSE Oral, Guiapax PSE Oral, Guiatex II SR Oral, Guiatex PSE Oral, Guiatuss PE Oral, Guiatussin Pe Oral, H 9600 SR Oral, Halotussin PE Oral, Harbertussin PE Oral, Histalet X Oral, Histex DA Oral, Hi-Tex Pse Oral, Iosal II Oral, Iotex PSE Oral, K-Gest Oral, Komatussin PE Oral, LEV/PSE/GG Oral, Levall G Oral, Liquitussin Severe Congestion Oral, Mardrops-EX Oral, Mastussin PE Oral, Maxifed (IR) Oral, Maxifed Oral, Maxifed-G (IR) Oral, Maxifed-G Oral, Medent LD Oral, Medent Oral, Medent-LDI Oral, Medi-Tussin PE Oral, Medi-Tussin Severe Congestion Oral, Med-Rx Oral, Mi-Decon Oral, Mindal Oral, Mintab D Oral, Miraphen PSE Oral, Mucinex D Maximum Strength Oral, Mucinex D Oral, Mucus Relief D (pseudoephed) Oral, Mytussin PE Oral, Nalex-CR Oral, Nalex-Jr Oral, Nasabid SR Oral, Nasatab LA Oral, Nomuc-PE Oral, PanMist JR Oral, PanMist LA Oral, PanMist S Oral, Poly-Vent IR Oral, Poly-Vent Jr Oral, Poly-Vent Oral, Profed Oral, Promist La Oral, PSE 120 Oral, PSE 60 Oral, Pseudatex Oral, Pseudo GG Oral, Pseudo GG TR Oral, Pseudo Max Oral, Pseudocot-G Oral, Pseudoephedrine GG Oral, Pseudoephedrine N-Drying Sinus Oral, Pseudoephedrine Non-Dry Sinus Oral, pseudoephedrine-guaifenesin/GG Oral, Pseudofen LA Oral, Pseudofenesin PSE Oral, Pseudofen-PD LA Oral, Pseudo-G Oral, Pseudo-G/PSI Oral, Pseudovent 400 Oral, Pseudovent Oral, Pseudovent Ped Oral, Q-Tussin PE -AF Oral, Q-Tussin PE Oral, Refenesen Plus Oral, Respa-1st Oral, Respaire-120 Oral, Respaire-30 Oral, Respaire-60 Oral, Respinol-G Oral, Respinol-La Oral, Robafen PE Oral, Robafen Severe Congestion Oral, Robichem Pe Oral, Robitussin PE Oral, Robitussin Severe Congestion Oral, Ru-Tuss DE Oral, Ru-Tuss Jr Oral, Rydex G Oral, Sinufed Oral, Sinumist Oral, Sinutab Non-Drying Oral, S-Pak Oral, STAMOIST E Oral, Sudafed Non-Drowsy Oral, Suda-G Oral, Sudal SR Oral, SudaTex G Oral, SudaTex Oral, SudaTex-G Oral, Suda-X Oral, Super Tussin PE Oral, Su-Phedrin Non Drying Sinus Oral, Suphedrin Non-Drying Sinus Oral, Sustex PSE Oral, Syn-Rx Oral, Tenar PSE Oral, TG 45PSE-400GFN Oral, Tidafen LA Oral, T-Moist Oral, Touro LA Oral, Touro LA-LD Oral, Triacting Chest & Nasal Cong Oral, Triacting Chest Congestion Oral, Triacting Citrus Oral, Tricomine Oral, Trispec Dex Oral, T-Tussin PE Oral, Tusscidin PE Oral, Tussin Cold Severe Congestion Oral, Tussin Ephedrine Oral, Tussin Severe Congestion Oral, Tussin Severe Oral, Tuss-La Oral, Uni-Tussin PE Oral, V-Dec-M Oral, Venbid TR Oral, Versacaps Oral, Wal-Tussin Cold Severe Congest Oral, We Mist II Oral, WE Mist LA Oral, Zaptec PSE Oral, Zephrex LA Oral, Zephrex Oral

All generic drug interactions for pseudoephedrine-guaifenesin oral (lists will include brand and generic names):

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  • No matching drugs found

Check for more interactions with the Drug Interaction Checker

Drug Interaction Categories


Never use this combination of drugs because of high risk for dangerous interaction


Potential for serious interaction; regular monitoring by your doctor required or alternate medication may be needed


Potential for significant interaction (monitoring by your doctor is likely required)


Interaction is unlikely, minor, or nonsignificant

Disclaimer: The information contained herein should NOT be used as a substitute for the advice of an appropriately qualified and licensed physician or other health care provider. The information provided here is for informational purposes only. This tool may not cover all possible drug interactions. Please check with a physician if you have health questions or concerns. Although we attempt to provide accurate and up-to-date information, no guarantee is made to that effect.

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